Dubey R - Search Results

1

Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling.

Griffiths SC, Schwab RA, El Omari K, Bishop B, Iverson EJ, Malinauskas T, Dubey R, Qian M, Covey DF, Gilbert RJC, Rohatgi R, Siebold C. Griffiths SC, et al. Among authors: dubey r. Nat Commun. 2021 Dec 9;12(1):7171. doi: 10.1038/s41467-021-27475-2. Nat Commun. 2021. PMID: 34887403 Free PMC article.

2

R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling.

Dubey R, van Kerkhof P, Jordens I, Malinauskas T, Pusapati GV, McKenna JK, Li D, Carette JE, Ho M, Siebold C, Maurice M, Lebensohn AM, Rohatgi R. Dubey R, et al. Elife. 2020 May 20;9:e54469. doi: 10.7554/eLife.54469. Elife. 2020. PMID: 32432544 Free PMC article.

3

Lipid droplets can promote drug accumulation and activation.

Dubey R, Stivala CE, Nguyen HQ, Goo YH, Paul A, Carette JE, Trost BM, Rohatgi R. Dubey R, et al. Nat Chem Biol. 2020 Feb;16(2):206-213. doi: 10.1038/s41589-019-0447-7. Epub 2020 Jan 13. Nat Chem Biol. 2020. PMID: 31932720 Free PMC article.

4

Chromatin-Remodeling Complex SWI/SNF Controls Multidrug Resistance by Transcriptionally Regulating the Drug Efflux Pump ABCB1.

Dubey R, Lebensohn AM, Bahrami-Nejad Z, Marceau C, Champion M, Gevaert O, Sikic BI, Carette JE, Rohatgi R. Dubey R, et al. Cancer Res. 2016 Oct 1;76(19):5810-5821. doi: 10.1158/0008-5472.CAN-16-0716. Epub 2016 Aug 8. Cancer Res. 2016. PMID: 27503929 Free PMC article.

5

Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling.

Lebensohn AM, Dubey R, Neitzel LR, Tacchelly-Benites O, Yang E, Marceau CD, Davis EM, Patel BB, Bahrami-Nejad Z, Travaglini KJ, Ahmed Y, Lee E, Carette JE, Rohatgi R. Lebensohn AM, et al. Among authors: dubey r. Elife. 2016 Dec 20;5:e21459. doi: 10.7554/eLife.21459. Elife. 2016. PMID: 27996937 Free PMC article.

6

Inhibition of hypoxia inducible factor 1-transcription coactivator interaction by a hydrogen bond surrogate alpha-helix.

Henchey LK, Kushal S, Dubey R, Chapman RN, Olenyuk BZ, Arora PS. Henchey LK, et al. Among authors: dubey r. J Am Chem Soc. 2010 Jan 27;132(3):941-3. doi: 10.1021/ja9082864. J Am Chem Soc. 2010. PMID: 20041650 Free PMC article.

7

Direct inhibition of hypoxia-inducible transcription factor complex with designed dimeric epidithiodiketopiperazine.

Block KM, Wang H, Szabó LZ, Polaske NW, Henchey LK, Dubey R, Kushal S, László CF, Makhoul J, Song Z, Meuillet EJ, Olenyuk BZ. Block KM, et al. Among authors: dubey r. J Am Chem Soc. 2009 Dec 23;131(50):18078-88. doi: 10.1021/ja807601b. J Am Chem Soc. 2009. PMID: 20000859 Free PMC article.

8

Suppression of tumor growth by designed dimeric epidithiodiketopiperazine targeting hypoxia-inducible transcription factor complex.

Dubey R, Levin MD, Szabo LZ, Laszlo CF, Kushal S, Singh JB, Oh P, Schnitzer JE, Olenyuk BZ. Dubey R, et al. J Am Chem Soc. 2013 Mar 20;135(11):4537-49. doi: 10.1021/ja400805b. Epub 2013 Mar 11. J Am Chem Soc. 2013. PMID: 23448368

9

Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling.

Kushal S, Lao BB, Henchey LK, Dubey R, Mesallati H, Traaseth NJ, Olenyuk BZ, Arora PS. Kushal S, et al. Among authors: dubey r. Proc Natl Acad Sci U S A. 2013 Sep 24;110(39):15602-7. doi: 10.1073/pnas.1312473110. Epub 2013 Sep 9. Proc Natl Acad Sci U S A. 2013. PMID: 24019500 Free PMC article.

10

Direct organocatalytic coupling of carboxylated piperazine-2,5-diones with indoles through conjugate addition of carbon nucleophiles to indolenine intermediates.

Dubey R, Olenyuk B. Dubey R, et al. Tetrahedron Lett. 2010 Jan 27;51(4):609-612. doi: 10.1016/j.tetlet.2009.11.068. Tetrahedron Lett. 2010. PMID: 20161551 Free PMC article.

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