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An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice.
Rohm M, Schäfer M, Laurent V, Üstünel BE, Niopek K, Algire C, Hautzinger O, Sijmonsma TP, Zota A, Medrikova D, Pellegata NS, Ryden M, Kulyte A, Dahlman I, Arner P, Petrovic N, Cannon B, Amri EZ, Kemp BE, Steinberg GR, Janovska P, Kopecky J, Wolfrum C, Blüher M, Berriel Diaz M, Herzig S. Rohm M, et al. Among authors: pellegata ns. Nat Med. 2016 Oct;22(10):1120-1130. doi: 10.1038/nm.4171. Epub 2016 Aug 29. Nat Med. 2016. PMID: 27571348
Angpt2/Tie2 autostimulatory loop controls tumorigenesis.
Karabid NM, Wiedemann T, Gulde S, Mohr H, Segaran RC, Geppert J, Rohm M, Vitale G, Gaudenzi G, Dicitore A, Ankerst DP, Chen Y, Braren R, Kaissis G, Schilling F, Schillmaier M, Eisenhofer G, Herzig S, Roncaroli F, Honegger JB, Pellegata NS. Karabid NM, et al. Among authors: pellegata ns. EMBO Mol Med. 2022 May 9;14(5):e14364. doi: 10.15252/emmm.202114364. Epub 2022 Mar 10. EMBO Mol Med. 2022. PMID: 35266635 Free PMC article.
Levels of p27 sensitize to dual PI3K/mTOR inhibition.
Lee M, Theodoropoulou M, Graw J, Roncaroli F, Zatelli MC, Pellegata NS. Lee M, et al. Among authors: pellegata ns. Mol Cancer Ther. 2011 Aug;10(8):1450-9. doi: 10.1158/1535-7163.MCT-11-0188. Epub 2011 Jun 6. Mol Cancer Ther. 2011. PMID: 21646547
Animal models of MEN1.
Mohr H, Pellegata NS. Mohr H, et al. Among authors: pellegata ns. Endocr Relat Cancer. 2017 Oct;24(10):T161-T177. doi: 10.1530/ERC-17-0249. Epub 2017 Jul 25. Endocr Relat Cancer. 2017. PMID: 28743793 Review.
Gender-Specific Efficacy Revealed by Head-to-Head Comparison of Pasireotide and Octreotide in a Representative In Vivo Model of Nonfunctioning Pituitary Tumors.
Gulde S, Wiedemann T, Schillmaier M, Valença I, Lupp A, Steiger K, Yen HY, Bäuerle S, Notni J, Luque R, Schmid H, Schulz S, Ankerst DP, Schilling F, Pellegata NS. Gulde S, et al. Among authors: pellegata ns. Cancers (Basel). 2021 Jun 21;13(12):3097. doi: 10.3390/cancers13123097. Cancers (Basel). 2021. PMID: 34205778 Free PMC article.
104 results