Pajvani UB - Search Results

1

TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis.

Wang X, Zeldin S, Shi H, Zhu C, Saito Y, Corey KE, Osganian SA, Remotti HE, Verna EC, Pajvani UB, Schwabe RF, Tabas I. Wang X, et al. Among authors: pajvani ub. J Hepatol. 2022 Apr;76(4):910-920. doi: 10.1016/j.jhep.2021.11.031. Epub 2021 Dec 11. J Hepatol. 2022. PMID: 34902531 Free PMC article.

2

Calcium signaling through CaMKII regulates hepatic glucose production in fasting and obesity.

Ozcan L, Wong CC, Li G, Xu T, Pajvani U, Park SK, Wronska A, Chen BX, Marks AR, Fukamizu A, Backs J, Singer HA, Yates JR 3rd, Accili D, Tabas I. Ozcan L, et al. Cell Metab. 2012 May 2;15(5):739-51. doi: 10.1016/j.cmet.2012.03.002. Epub 2012 Apr 12. Cell Metab. 2012. PMID: 22503562 Free PMC article.

3

Adipocyte-specific blockade of gamma-secretase, but not inhibition of Notch activity, reduces adipose insulin sensitivity.

Sparling DP, Yu J, Kim K, Zhu C, Brachs S, Birkenfeld AL, Pajvani UB. Sparling DP, et al. Among authors: pajvani ub. Mol Metab. 2015 Dec 2;5(2):113-121. doi: 10.1016/j.molmet.2015.11.006. eCollection 2016 Feb. Mol Metab. 2015. PMID: 26909319 Free PMC article.

4

Notch signaling dynamically regulates adult β cell proliferation and maturity.

Bartolome A, Zhu C, Sussel L, Pajvani UB. Bartolome A, et al. Among authors: pajvani ub. J Clin Invest. 2019 Jan 2;129(1):268-280. doi: 10.1172/JCI98098. Epub 2018 Dec 3. J Clin Invest. 2019. PMID: 30375986 Free PMC article.

5

Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis.

Zhu C, Kim K, Wang X, Bartolome A, Salomao M, Dongiovanni P, Meroni M, Graham MJ, Yates KP, Diehl AM, Schwabe RF, Tabas I, Valenti L, Lavine JE, Pajvani UB. Zhu C, et al. Among authors: pajvani ub. Sci Transl Med. 2018 Nov 21;10(468):eaat0344. doi: 10.1126/scitranslmed.aat0344. Sci Transl Med. 2018. PMID: 30463916 Free PMC article.

6

Mechanisms of Fibrosis Development in Nonalcoholic Steatohepatitis.

Schwabe RF, Tabas I, Pajvani UB. Schwabe RF, et al. Among authors: pajvani ub. Gastroenterology. 2020 May;158(7):1913-1928. doi: 10.1053/j.gastro.2019.11.311. Epub 2020 Feb 8. Gastroenterology. 2020. PMID: 32044315 Free PMC article. Review.

7

Inhibition of PU.1 ameliorates metabolic dysfunction and non-alcoholic steatohepatitis.

Liu Q, Yu J, Wang L, Tang Y, Zhou Q, Ji S, Wang Y, Santos L, Haeusler RA, Que J, Rajbhandari P, Lei X, Valenti L, Pajvani UB, Qin J, Qiang L. Liu Q, et al. Among authors: pajvani ub. J Hepatol. 2020 Aug;73(2):361-370. doi: 10.1016/j.jhep.2020.02.025. Epub 2020 Mar 3. J Hepatol. 2020. PMID: 32135178

8

Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis.

Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I. Wang X, et al. Among authors: pajvani ub. Cell Metab. 2020 May 5;31(5):969-986.e7. doi: 10.1016/j.cmet.2020.03.010. Epub 2020 Apr 6. Cell Metab. 2020. PMID: 32259482 Free PMC article.

9

Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis.

Richter LR, Wan Q, Wen D, Zhang Y, Yu J, Kang JK, Zhu C, McKinnon EL, Gu Z, Qiang L, Pajvani UB. Richter LR, et al. Among authors: pajvani ub. ACS Nano. 2020 Jun 23;14(6):6878-6886. doi: 10.1021/acsnano.0c01007. Epub 2020 May 22. ACS Nano. 2020. PMID: 32441510 Free PMC article.

10

Notch activity characterizes a common hepatocellular carcinoma subtype with unique molecular and clinicopathologic features.

Zhu C, Ho YJ, Salomao MA, Dapito DH, Bartolome A, Schwabe RF, Lee JS, Lowe SW, Pajvani UB. Zhu C, et al. Among authors: pajvani ub. J Hepatol. 2021 Mar;74(3):613-626. doi: 10.1016/j.jhep.2020.09.032. Epub 2020 Oct 8. J Hepatol. 2021. PMID: 33038431 Free PMC article.

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