Chen S - Search Results

1

Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.

Yang Y, Xu Y, Yue Y, Wang H, Cui Y, Pan M, Zhang X, Zhang L, Li H, Xu M, Tang Y, Chen S. Yang Y, et al. Among authors: chen s. ACS Chem Biol. 2022 Jan 21;17(1):39-53. doi: 10.1021/acschembio.1c00394. Epub 2021 Dec 15. ACS Chem Biol. 2022. PMID: 34908399

2

Re-discovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis.

Wang H, Xu M, Engelhart CA, Zhang X, Yan B, Pan M, Xu Y, Fan S, Liu R, Xu L, Hua L, Schnappinger D, Chen S. Wang H, et al. Among authors: chen s. J Biol Chem. 2021 Jan 4:jbc.RA120.016477. doi: 10.1074/jbc.RA120.016477. Online ahead of print. J Biol Chem. 2021. PMID: 33397709 Free article.

3

Rediscovery of PF-3845 as a new chemical scaffold inhibiting phenylalanyl-tRNA synthetase in Mycobacterium tuberculosis.

Wang H, Xu M, Engelhart CA, Zhang X, Yan B, Pan M, Xu Y, Fan S, Liu R, Xu L, Hua L, Schnappinger D, Chen S. Wang H, et al. Among authors: chen s. J Biol Chem. 2021 Jan-Jun;296:100257. doi: 10.1016/j.jbc.2021.100257. Epub 2021 Jan 8. J Biol Chem. 2021. PMID: 33837735 Free PMC article.

4

Human Kinase IGF1R/IR Inhibitor Linsitinib Controls the In Vitro and Intracellular Growth of Mycobacterium tuberculosis.

Wang H, Bi J, Zhang Y, Pan M, Guo Q, Xiao G, Cui Y, Hu S, Chan CK, Yuan Y, Kaneko T, Zhang G, Chen S. Wang H, et al. Among authors: chen s. ACS Infect Dis. 2022 Oct 14;8(10):2019-2027. doi: 10.1021/acsinfecdis.2c00278. Epub 2022 Sep 1. ACS Infect Dis. 2022. PMID: 36048501

5

Assessing Boron-Pleuromutilin AN11251 for the Development of Antibacterial Agents.

Han MJ, Pan M, Xiao G, Yuan Y, Chen S, Zou Z. Han MJ, et al. Among authors: chen s. Molecules. 2023 Jun 8;28(12):4628. doi: 10.3390/molecules28124628. Molecules. 2023. PMID: 37375183 Free PMC article.

6

Biosynthesis of albomycin δ(2) provides a template for assembling siderophore and aminoacyl-tRNA synthetase inhibitor conjugates.

Zeng Y, Kulkarni A, Yang Z, Patil PB, Zhou W, Chi X, Van Lanen S, Chen S. Zeng Y, et al. Among authors: chen s. ACS Chem Biol. 2012 Sep 21;7(9):1565-75. doi: 10.1021/cb300173x. Epub 2012 Jun 25. ACS Chem Biol. 2012. PMID: 22704654 Free PMC article.

7

Total synthesis and antimicrobial evaluation of natural albomycins against clinical pathogens.

Lin Z, Xu X, Zhao S, Yang X, Guo J, Zhang Q, Jing C, Chen S, He Y. Lin Z, et al. Among authors: chen s. Nat Commun. 2018 Sep 4;9(1):3445. doi: 10.1038/s41467-018-05821-1. Nat Commun. 2018. PMID: 30181560 Free PMC article.

8

Nature's combinatorial biosynthesis and recently engineered production of nucleoside antibiotics in Streptomyces.

Chen S, Kinney WA, Van Lanen S. Chen S, et al. World J Microbiol Biotechnol. 2017 Apr;33(4):66. doi: 10.1007/s11274-017-2233-6. Epub 2017 Mar 4. World J Microbiol Biotechnol. 2017. PMID: 28260195 Review.

9

A Branch Point of Streptomyces Sulfur Amino Acid Metabolism Controls the Production of Albomycin.

Kulkarni A, Zeng Y, Zhou W, Van Lanen S, Zhang W, Chen S. Kulkarni A, et al. Among authors: chen s. Appl Environ Microbiol. 2015 Oct 30;82(2):467-77. doi: 10.1128/AEM.02517-15. Print 2016 Jan 15. Appl Environ Microbiol. 2015. PMID: 26519385 Free PMC article.

10

Characterization of two seryl-tRNA synthetases in albomycin-producing Streptomyces sp. strain ATCC 700974.

Zeng Y, Roy H, Patil PB, Ibba M, Chen S. Zeng Y, et al. Among authors: chen s. Antimicrob Agents Chemother. 2009 Nov;53(11):4619-27. doi: 10.1128/AAC.00782-09. Epub 2009 Aug 31. Antimicrob Agents Chemother. 2009. PMID: 19721072 Free PMC article.

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