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Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease.
Kirkeby A, Nolbrant S, Tiklova K, Heuer A, Kee N, Cardoso T, Ottosson DR, Lelos MJ, Rifes P, Dunnett SB, Grealish S, Perlmann T, Parmar M. Kirkeby A, et al. Among authors: ottosson dr. Cell Stem Cell. 2017 Jan 5;20(1):135-148. doi: 10.1016/j.stem.2016.09.004. Epub 2016 Oct 27. Cell Stem Cell. 2017. PMID: 28094017 Free PMC article.
Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation.
Pircs K, Petri R, Madsen S, Brattås PL, Vuono R, Ottosson DR, St-Amour I, Hersbach BA, Matusiak-Brückner M, Lundh SH, Petersén Å, Déglon N, Hébert SS, Parmar M, Barker RA, Jakobsson J. Pircs K, et al. Among authors: ottosson dr. Cell Rep. 2018 Aug 7;24(6):1397-1406. doi: 10.1016/j.celrep.2018.07.017. Cell Rep. 2018. PMID: 30089251 Free article.
Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Pathology in the 6-OHDA Model of Parkinson's Disease.
Shrigley S, Nilsson F, Mattsson B, Fiorenzano A, Mudannayake J, Bruzelius A, Ottosson DR, Björklund A, Hoban DB, Parmar M. Shrigley S, et al. Among authors: ottosson dr. J Parkinsons Dis. 2021;11(2):515-528. doi: 10.3233/JPD-202366. J Parkinsons Dis. 2021. PMID: 33361611 Free PMC article.
Author Correction: Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids.
Fiorenzano A, Sozzi E, Birtele M, Kajtez J, Giacomoni J, Nilsson F, Bruzelius A, Sharma Y, Zhang Y, Mattsson B, Emnéus J, Ottosson DR, Storm P, Parmar M. Fiorenzano A, et al. Among authors: ottosson dr. Nat Commun. 2022 Jun 8;13(1):3312. doi: 10.1038/s41467-022-31024-w. Nat Commun. 2022. PMID: 35676291 Free PMC article. No abstract available.
Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease.
Drouin-Ouellet J, Legault EM, Nilsson F, Pircs K, Bouquety J, Petit F, Shrigley S, Birtele M, Pereira M, Storm P, Sharma Y, Bruzelius A, Vuono R, Kele M, Stoker TB, Ottosson DR, Falk A, Jakobsson J, Barker RA, Parmar M. Drouin-Ouellet J, et al. Among authors: ottosson dr. Stem Cell Reports. 2022 Oct 11;17(10):2203-2219. doi: 10.1016/j.stemcr.2022.08.010. Epub 2022 Sep 22. Stem Cell Reports. 2022. PMID: 36150382 Free PMC article.
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain.
Birtele M, Storm P, Sharma Y, Kajtez J, Wahlestedt JN, Sozzi E, Nilsson F, Stott S, He XL, Mattsson B, Ottosson DR, Barker RA, Fiorenzano A, Parmar M. Birtele M, et al. Among authors: ottosson dr. Development. 2022 Dec 1;149(23):dev200504. doi: 10.1242/dev.200504. Epub 2022 Dec 8. Development. 2022. PMID: 36305490 Free PMC article.
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