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Primary Tumor Suppression and Systemic Immune Activation of Macrophages through the Sting Pathway in Metastatic Skin Tumor.
Synn CB, Kim DK, Kim JH, Byeon Y, Kim YS, Yun MR, Lee JM, Lee W, Lee EJ, Lee S, Lee YW, Lee DJ, Kim HW, Kim CG, Hong MH, Park JD, Lim SM, Pyo KH. Synn CB, et al. Among authors: lee ej, lee w, lee dj, lee yw, lee jm, lee s. Yonsei Med J. 2022 Jan;63(1):42-55. doi: 10.3349/ymj.2022.63.1.42. Yonsei Med J. 2022. PMID: 34913283 Free PMC article.
Clinical decision support algorithm based on machine learning to assess the clinical response to anti-programmed death-1 therapy in patients with non-small-cell lung cancer.
Ahn BC, So JW, Synn CB, Kim TH, Kim JH, Byeon Y, Kim YS, Heo SG, Yang SD, Yun MR, Lim S, Choi SJ, Lee W, Kim DK, Lee EJ, Lee S, Lee DJ, Kim CG, Lim SM, Hong MH, Cho BC, Pyo KH, Kim HR. Ahn BC, et al. Among authors: lee ej, lee w, lee dj, lee s. Eur J Cancer. 2021 Aug;153:179-189. doi: 10.1016/j.ejca.2021.05.019. Epub 2021 Jun 26. Eur J Cancer. 2021. PMID: 34182269
SKI-G-801, an AXL kinase inhibitor, blocks metastasis through inducing anti-tumor immune responses and potentiates anti-PD-1 therapy in mouse cancer models.
Synn CB, Kim SE, Lee HK, Kim MH, Kim JH, Lee JM, Jo HN, Lee W, Kim DK, Byeon Y, Kim YS, Yun MR, Park CW, Yun J, Lim S, Heo SG, Yang SD, Lee EJ, Lee S, Choi H, Lee YW, Cho JS, Kim DH, Park S, Kim JH, Choi Y, Lee SS, Ahn BC, Kim CG, Lim SM, Hong MH, Kim HR, Pyo KH, Cho BC. Synn CB, et al. Among authors: lee ej, lee w, lee yw, lee ss, lee hk, lee jm, lee s. Clin Transl Immunology. 2021 Dec 29;11(1):e1364. doi: 10.1002/cti2.1364. eCollection 2022. Clin Transl Immunology. 2021. PMID: 35003748 Free PMC article.
Incorporation of SKI-G-801, a Novel AXL Inhibitor, With Anti-PD-1 Plus Chemotherapy Improves Anti-Tumor Activity and Survival by Enhancing T Cell Immunity.
Lee W, Kim DK, Synn CB, Lee HK, Park S, Jung DS, Choi Y, Kim JH, Byeon Y, Kim YS, Lee S, Lee S, Joo Y, Lee EJ, Yun MR, Heo SG, Yang W, Jung JE, Kim EK, Park J, Park JD, Lee DJ, Kim HW, Lim SM, Hong MH, Ahn BC, Lee JB, Pyo KH. Lee W, et al. Among authors: lee ej, lee dj, lee jb, lee hk, lee s. Front Oncol. 2022 Mar 9;12:821391. doi: 10.3389/fonc.2022.821391. eCollection 2022. Front Oncol. 2022. PMID: 35356198 Free PMC article.
Denfivontinib activates effector T-cells through NLRP3-inflammasome, yielding potent anticancer effects by combination with pembrolizumab.
Kim DK, Synn CB, Lee W, Jo HN, Lee CY, Lee S, Hwang JY, Kim Y, Kang SS, Baek S, Na K, Yang SM, Kim MH, Han H, Han YJ, Kim JH, Park SY, Park YJ, Lee GT, Choi SJ, Sohn JO, Ye SK, Lee JB, Lim SM, Hong MH, Pyo KH, Cho BC. Kim DK, et al. Among authors: lee w, lee cy, lee jb, lee gt, lee s. Mol Cancer Ther. 2024 Dec 5. doi: 10.1158/1535-7163.MCT-24-0501. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39632711
Drug Development.
Kim H, Yoon JK, Lee W, Jeon M, Lee H, Kang S, Kang ES, Lee JE, Kim S, Rho HS, Levey AI, Kim Y. Kim H, et al. Among authors: lee w. Alzheimers Dement. 2024 Dec;20 Suppl 6:e088444. doi: 10.1002/alz.088444. Alzheimers Dement. 2024. PMID: 39782632
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