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Page 1
Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.
Wellaway CR, Baldwin IR, Bamborough P, Barker D, Bartholomew MA, Chung CW, Dümpelfeld B, Evans JP, Fazakerley NJ, Homes P, Keeling SP, Lewell XQ, McNab FW, Morley J, Needham D, Neu M, van Oosterhout AJM, Pal A, Reinhard FBM, Rianjongdee F, Robertson CM, Rowland P, Shah RR, Sherriff EB, Sloan LA, Teague S, Thomas DA, Wellaway N, Wojno-Picon J, Woolven JM, Coe DM. Wellaway CR, et al. Among authors: mcnab fw. J Med Chem. 2022 Jan 13;65(1):633-664. doi: 10.1021/acs.jmedchem.1c01765. Epub 2021 Dec 20. J Med Chem. 2022. PMID: 34928601
Type I IFN Inhibits Alternative Macrophage Activation during Mycobacterium tuberculosis Infection and Leads to Enhanced Protection in the Absence of IFN-γ Signaling.
Moreira-Teixeira L, Sousa J, McNab FW, Torrado E, Cardoso F, Machado H, Castro F, Cardoso V, Gaifem J, Wu X, Appelberg R, Castro AG, O'Garra A, Saraiva M. Moreira-Teixeira L, et al. Among authors: mcnab fw. J Immunol. 2016 Dec 15;197(12):4714-4726. doi: 10.4049/jimmunol.1600584. Epub 2016 Nov 14. J Immunol. 2016. PMID: 27849167 Free PMC article.
Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling.
Pitt JM, Blankley S, Potempa K, Graham CM, Moreira-Teixeira L, McNab FW, Howes A, Stavropoulos E, Pascual V, Banchereau J, Chaussabel D, O'Garra A. Pitt JM, et al. Among authors: mcnab fw. PLoS One. 2016 Feb 26;11(2):e0150251. doi: 10.1371/journal.pone.0150251. eCollection 2016. PLoS One. 2016. PMID: 26918359 Free PMC article.
The immune response in tuberculosis.
O'Garra A, Redford PS, McNab FW, Bloom CI, Wilkinson RJ, Berry MP. O'Garra A, et al. Among authors: mcnab fw. Annu Rev Immunol. 2013;31:475-527. doi: 10.1146/annurev-immunol-032712-095939. Annu Rev Immunol. 2013. PMID: 23516984 Review.
Tripartite-motif proteins and innate immune regulation.
McNab FW, Rajsbaum R, Stoye JP, O'Garra A. McNab FW, et al. Curr Opin Immunol. 2011 Feb;23(1):46-56. doi: 10.1016/j.coi.2010.10.021. Epub 2010 Dec 3. Curr Opin Immunol. 2011. PMID: 21131187 Review.
16 results