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A scalable assessment of Plasmodium falciparum transmission in the standard membrane-feeding assay, using transgenic parasites expressing green fluorescent protein-luciferase.
Stone WJ, Churcher TS, Graumans W, van Gemert GJ, Vos MW, Lanke KH, van de Vegte-Bolmer MG, Siebelink-Stoter R, Dechering KJ, Vaughan AM, Camargo N, Kappe SH, Sauerwein RW, Bousema T. Stone WJ, et al. Among authors: vos mw. J Infect Dis. 2014 Nov 1;210(9):1456-63. doi: 10.1093/infdis/jiu271. Epub 2014 May 14. J Infect Dis. 2014. PMID: 24829466
Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum.
Schalkwijk J, Allman EL, Jansen PAM, de Vries LE, Verhoef JMJ, Jackowski S, Botman PNM, Beuckens-Schortinghuis CA, Koolen KMJ, Bolscher JM, Vos MW, Miller K, Reeves SA, Pett H, Trevitt G, Wittlin S, Scheurer C, Sax S, Fischli C, Angulo-Barturen I, Jiménez-Diaz MB, Josling G, Kooij TWA, Bonnert R, Campo B, Blaauw RH, Rutjes FPJT, Sauerwein RW, Llinás M, Hermkens PHH, Dechering KJ. Schalkwijk J, et al. Among authors: vos mw. Sci Transl Med. 2019 Sep 18;11(510):eaas9917. doi: 10.1126/scitranslmed.aas9917. Sci Transl Med. 2019. PMID: 31534021
Replenishing the malaria drug discovery pipeline: Screening and hit evaluation of the MMV Hit Generation Library 1 (HGL1) against asexual blood stage Plasmodium falciparum, using a nano luciferase reporter read-out.
Dechering KJ, Timmerman M, Rensen K, Koolen KMJ, Honarnejad S, Vos MW, Huijs T, Henderson RWM, Chenu E, Laleu B, Montefiore BC, Segall MD, Mills JEJ, Guantai EM, Duffy J, Duffey M. Dechering KJ, et al. Among authors: vos mw. SLAS Discov. 2022 Sep;27(6):337-348. doi: 10.1016/j.slasd.2022.07.002. Epub 2022 Jul 21. SLAS Discov. 2022. PMID: 35872229 Free article.
Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes.
Fabra-García A, Hailemariam S, de Jong RM, Janssen K, Teelen K, van de Vegte-Bolmer M, van Gemert GJ, Ivanochko D, Semesi A, McLeod B, Vos MW, de Bruijni MHC, Bolscher JM, Szabat M, Vogt S, Kraft L, Duncan S, Kamya MR, Feeney ME, Jagannathan P, Greenhouse B, Dechering KJ, Sauerwein RW, King CR, MacGill RS, Bousema T, Julien JP, Jore MM. Fabra-García A, et al. Among authors: vos mw. Immunity. 2023 Feb 14;56(2):406-419.e7. doi: 10.1016/j.immuni.2023.01.009. Immunity. 2023. PMID: 36792574 Free PMC article.
19 results