Pratt MR - Search Results

1

4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase.

Jackson EG, Cutolo G, Yang B, Yarravarapu N, Burns MWN, Bineva-Todd G, Roustan C, Thoden JB, Lin-Jones HM, van Kuppevelt TH, Holden HM, Schumann B, Kohler JJ, Woo CM, Pratt MR. Jackson EG, et al. Among authors: pratt mr. ACS Chem Biol. 2022 Jan 21;17(1):159-170. doi: 10.1021/acschembio.1c00818. Epub 2021 Dec 21. ACS Chem Biol. 2022. PMID: 34931806 Free PMC article.

2

Chemical reporter for visualizing metabolic cross-talk between carbohydrate metabolism and protein modification.

Zaro BW, Chuh KN, Pratt MR. Zaro BW, et al. Among authors: pratt mr. ACS Chem Biol. 2014 Sep 19;9(9):1991-6. doi: 10.1021/cb5005564. Epub 2014 Jul 29. ACS Chem Biol. 2014. PMID: 25062036 Free PMC article.

3

Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.

Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR. Chuh KN, et al. Among authors: pratt mr. J Am Chem Soc. 2014 Sep 3;136(35):12283-95. doi: 10.1021/ja504063c. Epub 2014 Aug 25. J Am Chem Soc. 2014. PMID: 25153642 Free PMC article.

4

Synthesis of a Bis-thio-acetone (BTA) Analogue of the Lysine Isopeptide Bond and its Application to Investigate the Effects of Ubiquitination and SUMOylation on α-Synuclein Aggregation and Toxicity.

Lewis YE, Abeywardana T, Lin YH, Galesic A, Pratt MR. Lewis YE, et al. Among authors: pratt mr. ACS Chem Biol. 2016 Apr 15;11(4):931-42. doi: 10.1021/acschembio.5b01042. Epub 2016 Jan 12. ACS Chem Biol. 2016. PMID: 26726734 Free PMC article.

5

The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase.

Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR. Zaro BW, et al. Among authors: pratt mr. ACS Chem Biol. 2017 Mar 17;12(3):787-794. doi: 10.1021/acschembio.6b00877. Epub 2017 Jan 30. ACS Chem Biol. 2017. PMID: 28135057 Free PMC article.

6

O-GlcNAcylation of α-Synuclein at Serine 87 Reduces Aggregation without Affecting Membrane Binding.

Lewis YE, Galesic A, Levine PM, De Leon CA, Lamiri N, Brennan CK, Pratt MR. Lewis YE, et al. Among authors: pratt mr. ACS Chem Biol. 2017 Apr 21;12(4):1020-1027. doi: 10.1021/acschembio.7b00113. Epub 2017 Feb 22. ACS Chem Biol. 2017. PMID: 28195695 Free PMC article.

7

Metabolic Chemical Reporters of Glycans Exhibit Cell-Type-Selective Metabolism and Glycoprotein Labeling.

Batt AR, Zaro BW, Navarro MX, Pratt MR. Batt AR, et al. Among authors: pratt mr. Chembiochem. 2017 Jul 4;18(13):1177-1182. doi: 10.1002/cbic.201700020. Epub 2017 Mar 28. Chembiochem. 2017. PMID: 28231413 Free PMC article.

8

The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.

Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR. Chuh KN, et al. Among authors: pratt mr. J Am Chem Soc. 2017 Jun 14;139(23):7872-7885. doi: 10.1021/jacs.7b02213. Epub 2017 May 31. J Am Chem Soc. 2017. PMID: 28528544 Free PMC article.

9

The Metabolic Chemical Reporter 6-Azido-6-deoxy-glucose Further Reveals the Substrate Promiscuity of O-GlcNAc Transferase and Catalyzes the Discovery of Intracellular Protein Modification by O-Glucose.

Darabedian N, Gao J, Chuh KN, Woo CM, Pratt MR. Darabedian N, et al. Among authors: pratt mr. J Am Chem Soc. 2018 Jun 13;140(23):7092-7100. doi: 10.1021/jacs.7b13488. Epub 2018 May 30. J Am Chem Soc. 2018. PMID: 29771506 Free PMC article.

10

Azide- and Alkyne-Bearing Metabolic Chemical Reporters of Glycosylation Show Structure-Dependent Feedback Inhibition of the Hexosamine Biosynthetic Pathway.

Walter LA, Batt AR, Darabedian N, Zaro BW, Pratt MR. Walter LA, et al. Among authors: pratt mr. Chembiochem. 2018 Sep 17;19(18):1918-1921. doi: 10.1002/cbic.201800280. Epub 2018 Aug 10. Chembiochem. 2018. PMID: 29979493 Free PMC article.

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