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4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase.
Jackson EG, Cutolo G, Yang B, Yarravarapu N, Burns MWN, Bineva-Todd G, Roustan C, Thoden JB, Lin-Jones HM, van Kuppevelt TH, Holden HM, Schumann B, Kohler JJ, Woo CM, Pratt MR. Jackson EG, et al. Among authors: van kuppevelt th. ACS Chem Biol. 2022 Jan 21;17(1):159-170. doi: 10.1021/acschembio.1c00818. Epub 2021 Dec 21. ACS Chem Biol. 2022. PMID: 34931806 Free PMC article.
Interfering with UDP-GlcNAc metabolism and heparan sulfate expression using a sugar analogue reduces angiogenesis.
van Wijk XM, Thijssen VL, Lawrence R, van den Broek SA, Dona M, Naidu N, Oosterhof A, van de Westerlo EM, Kusters LJ, Khaled Y, Jokela TA, Nowak-Sliwinska P, Kremer H, Stringer SE, Griffioen AW, van Wijk E, van Delft FL, van Kuppevelt TH. van Wijk XM, et al. Among authors: van kuppevelt th, van den broek sa, van delft fl, van de westerlo em, van wijk e. ACS Chem Biol. 2013 Oct 18;8(10):2331-8. doi: 10.1021/cb4004332. Epub 2013 Sep 3. ACS Chem Biol. 2013. PMID: 23972127 Free PMC article.
Sialic Acid Glycoengineering Using an Unnatural Sialic Acid for the Detection of Sialoglycan Biosynthesis Defects and On-Cell Synthesis of Siglec Ligands.
Büll C, Heise T, Beurskens DM, Riemersma M, Ashikov A, Rutjes FP, van Kuppevelt TH, Lefeber DJ, den Brok MH, Adema GJ, Boltje TJ. Büll C, et al. Among authors: van kuppevelt th. ACS Chem Biol. 2015 Oct 16;10(10):2353-63. doi: 10.1021/acschembio.5b00501. Epub 2015 Aug 10. ACS Chem Biol. 2015. PMID: 26258433
Detection of 2-O-sulfated iduronate and N-acetylglucosamine units in heparan sulfate by an antibody selected against acharan sulfate (IdoA2S-GlcNAc)n.
ten Dam GB, van de Westerlo EM, Smetsers TF, Willemse M, van Muijen GN, Merry CL, Gallagher JT, Kim YS, van Kuppevelt TH. ten Dam GB, et al. Among authors: van kuppevelt th, van de westerlo em, van muijen gn. J Biol Chem. 2004 Sep 10;279(37):38346-52. doi: 10.1074/jbc.M404166200. Epub 2004 Jul 7. J Biol Chem. 2004. PMID: 15247295 Free article.
A common sugar-nucleotide-mediated mechanism of inhibition of (glycosamino)glycan biosynthesis, as evidenced by 6F-GalNAc (Ac3).
van Wijk XM, Lawrence R, Thijssen VL, van den Broek SA, Troost R, van Scherpenzeel M, Naidu N, Oosterhof A, Griffioen AW, Lefeber DJ, van Delft FL, van Kuppevelt TH. van Wijk XM, et al. Among authors: van kuppevelt th, van den broek sa, van delft fl, van scherpenzeel m. FASEB J. 2015 Jul;29(7):2993-3002. doi: 10.1096/fj.14-264226. Epub 2015 Apr 13. FASEB J. 2015. PMID: 25868729 Free PMC article.
367 results