Zhu HJ - Search Results

1

Contributions of Cathepsin A and Carboxylesterase 1 to the Hydrolysis of Tenofovir Alafenamide in the Human Liver, and the Effect of CES1 Genetic Variation on Tenofovir Alafenamide Hydrolysis.

Li J, Shi J, Xiao J, Tran L, Wang X, Zhu HJ. Li J, et al. Among authors: zhu hj. Drug Metab Dispos. 2022 Mar;50(3):243-248. doi: 10.1124/dmd.120.000323. Epub 2021 Dec 21. Drug Metab Dispos. 2022. PMID: 34933885 Free PMC article.

2

Activation of the antiviral prodrug oseltamivir is impaired by two newly identified carboxylesterase 1 variants.

Zhu HJ, Markowitz JS. Zhu HJ, et al. Drug Metab Dispos. 2009 Feb;37(2):264-7. doi: 10.1124/dmd.108.024943. Epub 2008 Nov 20. Drug Metab Dispos. 2009. PMID: 19022936

3

Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril.

Zhu HJ, Appel DI, Johnson JA, Chavin KD, Markowitz JS. Zhu HJ, et al. Biochem Pharmacol. 2009 Apr 1;77(7):1266-72. doi: 10.1016/j.bcp.2008.12.017. Epub 2009 Jan 6. Biochem Pharmacol. 2009. PMID: 19185566

4

Age- and sex-related expression and activity of carboxylesterase 1 and 2 in mouse and human liver.

Zhu HJ, Appel DI, Jiang Y, Markowitz JS. Zhu HJ, et al. Drug Metab Dispos. 2009 Sep;37(9):1819-25. doi: 10.1124/dmd.109.028209. Epub 2009 Jun 1. Drug Metab Dispos. 2009. PMID: 19487248

5

Carboxylesterase 1 as a determinant of clopidogrel metabolism and activation.

Zhu HJ, Wang X, Gawronski BE, Brinda BJ, Angiolillo DJ, Markowitz JS. Zhu HJ, et al. J Pharmacol Exp Ther. 2013 Mar;344(3):665-72. doi: 10.1124/jpet.112.201640. Epub 2012 Dec 28. J Pharmacol Exp Ther. 2013. PMID: 23275066

6

The influence of the CYP2C19*10 allele on clopidogrel activation and CYP2C19*2 genotyping.

Langaee TY, Zhu HJ, Wang X, El Rouby N, Markowitz JS, Goldstein JA, Johnson JA. Langaee TY, et al. Among authors: zhu hj. Pharmacogenet Genomics. 2014 Aug;24(8):381-6. doi: 10.1097/FPC.0000000000000068. Pharmacogenet Genomics. 2014. PMID: 24945780 Free PMC article.

7

An ex vivo approach to botanical-drug interactions: a proof of concept study.

Wang X, Zhu HJ, Munoz J, Gurley BJ, Markowitz JS. Wang X, et al. Among authors: zhu hj. J Ethnopharmacol. 2015 Apr 2;163:149-56. doi: 10.1016/j.jep.2015.01.021. Epub 2015 Jan 24. J Ethnopharmacol. 2015. PMID: 25623616 Free PMC article.

8

Carboxylesterase 1-mediated drug-drug interactions between clopidogrel and simvastatin.

Wang X, Zhu HJ, Markowitz JS. Wang X, et al. Among authors: zhu hj. Biol Pharm Bull. 2015;38(2):292-7. doi: 10.1248/bpb.b14-00679. Biol Pharm Bull. 2015. PMID: 25747989 Free article.

9

Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation.

Shi J, Wang X, Nguyen J, Wu AH, Bleske BE, Zhu HJ. Shi J, et al. Among authors: zhu hj. Drug Metab Dispos. 2016 Apr;44(4):554-9. doi: 10.1124/dmd.115.068536. Epub 2016 Jan 27. Drug Metab Dispos. 2016. PMID: 26817948 Free PMC article.

10

Targeted absolute quantitative proteomics with SILAC internal standards and unlabeled full-length protein calibrators (TAQSI).

Wang X, Liang Y, Liu L, Shi J, Zhu HJ. Wang X, et al. Among authors: zhu hj. Rapid Commun Mass Spectrom. 2016 Mar 15;30(5):553-61. doi: 10.1002/rcm.7482. Rapid Commun Mass Spectrom. 2016. PMID: 26842578 Free PMC article.

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