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Page 1
Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta.
Ulrich L, Halwe NJ, Taddeo A, Ebert N, Schön J, Devisme C, Trüeb BS, Hoffmann B, Wider M, Fan X, Bekliz M, Essaidi-Laziosi M, Schmidt ML, Niemeyer D, Corman VM, Kraft A, Godel A, Laloli L, Kelly JN, Calderon BM, Breithaupt A, Wylezich C, Berenguer Veiga I, Gultom M, Osman S, Zhou B, Adea K, Meyer B, Eberhardt CS, Thomann L, Gsell M, Labroussaa F, Jores J, Summerfield A, Drosten C, Eckerle IA, Wentworth DE, Dijkman R, Hoffmann D, Thiel V, Beer M, Benarafa C. Ulrich L, et al. Among authors: halwe nj. Nature. 2022 Feb;602(7896):307-313. doi: 10.1038/s41586-021-04342-0. Epub 2021 Dec 22. Nature. 2022. PMID: 34937050 Free PMC article.
SARS-CoV-2 spike D614G change enhances replication and transmission.
Zhou B, Thao TTN, Hoffmann D, Taddeo A, Ebert N, Labroussaa F, Pohlmann A, King J, Steiner S, Kelly JN, Portmann J, Halwe NJ, Ulrich L, Trüeb BS, Fan X, Hoffmann B, Wang L, Thomann L, Lin X, Stalder H, Pozzi B, de Brot S, Jiang N, Cui D, Hossain J, Wilson MM, Keller MW, Stark TJ, Barnes JR, Dijkman R, Jores J, Benarafa C, Wentworth DE, Thiel V, Beer M. Zhou B, et al. Among authors: halwe nj. Nature. 2021 Apr;592(7852):122-127. doi: 10.1038/s41586-021-03361-1. Epub 2021 Feb 26. Nature. 2021. PMID: 33636719
CVnCoV and CV2CoV protect human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2.
Hoffmann D, Corleis B, Rauch S, Roth N, Mühe J, Halwe NJ, Ulrich L, Fricke C, Schön J, Kraft A, Breithaupt A, Wernike K, Michelitsch A, Sick F, Wylezich C, Hoffmann B, Thran M, Thess A, Mueller SO, Mettenleiter TC, Petsch B, Dorhoi A, Beer M. Hoffmann D, et al. Among authors: halwe nj. Nat Commun. 2021 Jun 30;12(1):4048. doi: 10.1038/s41467-021-24339-7. Nat Commun. 2021. PMID: 34193869 Free PMC article.
The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype.
Barut GT, Halwe NJ, Taddeo A, Kelly JN, Schön J, Ebert N, Ulrich L, Devisme C, Steiner S, Trüeb BS, Hoffmann B, Veiga IB, Leborgne NGF, Moreira EA, Breithaupt A, Wylezich C, Höper D, Wernike K, Godel A, Thomann L, Flück V, Stalder H, Brügger M, Esteves BIO, Zumkehr B, Beilleau G, Kratzel A, Schmied K, Ochsenbein S, Lang RM, Wider M, Machahua C, Dorn P, Marti TM, Funke-Chambour M, Rauch A, Widera M, Ciesek S, Dijkman R, Hoffmann D, Alves MP, Benarafa C, Beer M, Thiel V. Barut GT, et al. Among authors: halwe nj. Nat Commun. 2022 Oct 7;13(1):5929. doi: 10.1038/s41467-022-33632-y. Nat Commun. 2022. PMID: 36207334 Free PMC article.
Experimental SARS-CoV-2 Infection of Bank Voles.
Ulrich L, Michelitsch A, Halwe N, Wernike K, Hoffmann D, Beer M. Ulrich L, et al. Emerg Infect Dis. 2021 Apr;27(4):1193-1195. doi: 10.3201/eid2704.204945. Emerg Infect Dis. 2021. PMID: 33754987 Free PMC article.
SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility.
Zhou B, Thao TTN, Hoffmann D, Taddeo A, Ebert N, Labroussaa F, Pohlmann A, King J, Portmann J, Halwe NJ, Ulrich L, Trüeb BS, Kelly JN, Fan X, Hoffmann B, Steiner S, Wang L, Thomann L, Lin X, Stalder H, Pozzi B, de Brot S, Jiang N, Cui D, Hossain J, Wilson M, Keller M, Stark TJ, Barnes JR, Dijkman R, Jores J, Benarafa C, Wentworth DE, Thiel V, Beer M. Zhou B, et al. Among authors: halwe nj. bioRxiv [Preprint]. 2020 Oct 27:2020.10.27.357558. doi: 10.1101/2020.10.27.357558. bioRxiv. 2020. Update in: Nature. 2021 Apr;592(7852):122-127. doi: 10.1038/s41586-021-03361-1 PMID: 33140052 Free PMC article. Updated. Preprint.
Egyptian Fruit Bats (Rousettus aegyptiacus) Were Resistant to Experimental Inoculation with Avian-Origin Influenza A Virus of Subtype H9N2, But Are Susceptible to Experimental Infection with Bat-Borne H9N2 Virus.
Halwe NJ, Gorka M, Hoffmann B, Rissmann M, Breithaupt A, Schwemmle M, Beer M, Kandeil A, Ali MA, Kayali G, Hoffmann D, Balkema-Buschmann A. Halwe NJ, et al. Viruses. 2021 Apr 14;13(4):672. doi: 10.3390/v13040672. Viruses. 2021. PMID: 33919890 Free PMC article.
High protection and transmission-blocking immunity elicited by single-cycle SARS-CoV-2 vaccine in hamsters.
Lett MJ, Otte F, Hauser D, Schön J, Kipfer ET, Hoffmann D, Halwe NJ, Breithaupt A, Ulrich L, Britzke T, Kochmann J, Corleis B, Zhang Y, Urda L, Cmiljanovic V, Lang C, Beer M, Mittelholzer C, Klimkait T. Lett MJ, et al. Among authors: halwe nj. NPJ Vaccines. 2024 Oct 30;9(1):206. doi: 10.1038/s41541-024-00992-z. NPJ Vaccines. 2024. PMID: 39472701 Free PMC article.
H5N1 clade 2.3.4.4b dynamics in experimentally infected calves and cows.
Halwe NJ, Cool K, Breithaupt A, Schön J, Trujillo JD, Nooruzzaman M, Kwon T, Ahrens AK, Britzke T, McDowell CD, Piesche R, Singh G, Pinho Dos Reis V, Kafle S, Pohlmann A, Gaudreault NN, Corleis B, Ferreyra FM, Carossino M, Balasuriya UBR, Hensley L, Morozov I, Covaleda LM, Diel DG, Ulrich L, Hoffmann D, Beer M, Richt JA. Halwe NJ, et al. Nature. 2024 Sep 25. doi: 10.1038/s41586-024-08063-y. Online ahead of print. Nature. 2024. PMID: 39321846
Outcome of H5N1 clade 2.3.4.4b virus infection in calves and lactating cows.
Halwe NJ, Cool K, Breithaupt A, Schön J, Trujillo JD, Nooruzzaman M, Kwon T, Ahrens AK, Britzke T, McDowell CD, Piesche R, Singh G, Dos Reis VP, Kafle S, Pohlmann A, Gaudreault NN, Corleis B, Ferreyra FM, Carossino M, Balasuriya UBR, Hensley L, Morozov I, Covaleda LM, Diel D, Ulrich L, Hoffmann D, Beer M, Richt JA. Halwe NJ, et al. bioRxiv [Preprint]. 2024 Aug 9:2024.08.09.607272. doi: 10.1101/2024.08.09.607272. bioRxiv. 2024. PMID: 39149352 Free PMC article. Preprint.
17 results