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Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19.
Roukens AHE, Pothast CR, König M, Huisman W, Dalebout T, Tak T, Azimi S, Kruize Y, Hagedoorn RS, Zlei M, Staal FJT, de Bie FJ, van Dongen JJM, Arbous SM, Zhang JLH, Verheij M, Prins C, van der Does AM, Hiemstra PS, de Vries JJC, Janse JJ, Roestenberg M, Myeni SK, Kikkert M, Yazdanbakhsh M, Heemskerk MHM, Smits HH, Jochems SP; in collaboration with BEAT-COVID group; in collaboration with COVID-19 LUMC group. Roukens AHE, et al. Among authors: hagedoorn rs. Nat Immunol. 2022 Jan;23(1):23-32. doi: 10.1038/s41590-021-01095-w. Epub 2021 Dec 22. Nat Immunol. 2022. PMID: 34937933
Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application.
Griffioen M, van Egmond HM, Barnby-Porritt H, van der Hoorn MA, Hagedoorn RS, Kester MG, Schwabe N, Willemze R, Falkenburg JH, Heemskerk MH. Griffioen M, et al. Among authors: hagedoorn rs. Haematologica. 2008 Oct;93(10):1535-43. doi: 10.3324/haematol.13067. Epub 2008 Sep 2. Haematologica. 2008. PMID: 18768532 Free article.
Allo-HLA reactivity of virus-specific memory T cells is common.
Amir AL, D'Orsogna LJ, Roelen DL, van Loenen MM, Hagedoorn RS, de Boer R, van der Hoorn MA, Kester MG, Doxiadis II, Falkenburg JH, Claas FH, Heemskerk MH. Amir AL, et al. Among authors: hagedoorn rs. Blood. 2010 Apr 15;115(15):3146-57. doi: 10.1182/blood-2009-07-234906. Epub 2010 Feb 16. Blood. 2010. PMID: 20160165 Free article.
Mixed T cell receptor dimers harbor potentially harmful neoreactivity.
van Loenen MM, de Boer R, Amir AL, Hagedoorn RS, Volbeda GL, Willemze R, van Rood JJ, Falkenburg JH, Heemskerk MH. van Loenen MM, et al. Among authors: hagedoorn rs. Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):10972-7. doi: 10.1073/pnas.1005802107. Epub 2010 Jun 1. Proc Natl Acad Sci U S A. 2010. PMID: 20534461 Free PMC article.
47 results