Chou CJ - Search Results

1

Potent Hydrazide-Based HDAC Inhibitors with a Superior Pharmacokinetic Profile for Efficient Treatment of Acute Myeloid Leukemia In Vivo.

Jiang Y, Xu J, Yue K, Huang C, Qin M, Chi D, Yu Q, Zhu Y, Hou X, Xu T, Li M, Chou CJ, Li X. Jiang Y, et al. Among authors: chou cj. J Med Chem. 2022 Jan 13;65(1):285-302. doi: 10.1021/acs.jmedchem.1c01472. Epub 2021 Dec 23. J Med Chem. 2022. PMID: 34942071

2

Structure-activity relationship study of vitamin k derivatives yields highly potent neuroprotective agents.

Josey BJ, Inks ES, Wen X, Chou CJ. Josey BJ, et al. Among authors: chou cj. J Med Chem. 2013 Feb 14;56(3):1007-22. doi: 10.1021/jm301485d. Epub 2013 Jan 30. J Med Chem. 2013. PMID: 23327468 Free PMC article.

3

Discovery of the first N-hydroxycinnamamide-based histone deacetylase 1/3 dual inhibitors with potent oral antitumor activity.

Li X, Inks ES, Li X, Hou J, Chou CJ, Zhang J, Jiang Y, Zhang Y, Xu W. Li X, et al. Among authors: chou cj. J Med Chem. 2014 Apr 24;57(8):3324-41. doi: 10.1021/jm401877m. Epub 2014 Apr 15. J Med Chem. 2014. PMID: 24694055 Free PMC article.

4

Design, synthesis, and antitumor evaluation of novel histone deacetylase inhibitors equipped with a phenylsulfonylfuroxan module as a nitric oxide donor.

Duan W, Li J, Inks ES, Chou CJ, Jia Y, Chu X, Li X, Xu W, Zhang Y. Duan W, et al. Among authors: chou cj. J Med Chem. 2015 May 28;58(10):4325-38. doi: 10.1021/acs.jmedchem.5b00317. Epub 2015 May 7. J Med Chem. 2015. PMID: 25906087 Free PMC article.

5

Correction to Design, Synthesis, and Antitumor Evaluation of Novel Histone Deacetylase Inhibitors Equipped with a Phenylsulfonylfuroxan Module as a Nitric Oxide Donor.

Duan W, Li J, Inks ES, Chou CJ, Jia Y, Chu X, Li X, Xu W, Zhang Y. Duan W, et al. Among authors: chou cj. J Med Chem. 2015 Aug 13;58(15):6319. doi: 10.1021/acs.jmedchem.5b01075. Epub 2015 Jul 30. J Med Chem. 2015. PMID: 26225799 No abstract available.

6

Development of Allosteric Hydrazide-Containing Class I Histone Deacetylase Inhibitors for Use in Acute Myeloid Leukemia.

McClure JJ, Zhang C, Inks ES, Peterson YK, Li J, Chou CJ. McClure JJ, et al. Among authors: chou cj. J Med Chem. 2016 Nov 10;59(21):9942-9959. doi: 10.1021/acs.jmedchem.6b01385. Epub 2016 Oct 26. J Med Chem. 2016. PMID: 27754681 Free PMC article.

7

Selective HDAC inhibitors with potent oral activity against leukemia and colorectal cancer: Design, structure-activity relationship and anti-tumor activity study.

Li X, Zhang Y, Jiang Y, Wu J, Inks ES, Chou CJ, Gao S, Hou J, Ding Q, Li J, Wang X, Huang Y, Xu W. Li X, et al. Among authors: chou cj. Eur J Med Chem. 2017 Jul 7;134:185-206. doi: 10.1016/j.ejmech.2017.03.069. Epub 2017 Mar 30. Eur J Med Chem. 2017. PMID: 28415009 Free PMC article.

8

Design, synthesis and anti-tumor activity study of novel histone deacetylase inhibitors containing isatin-based caps and o-phenylenediamine-based zinc binding groups.

Gao S, Zang J, Gao Q, Liang X, Ding Q, Li X, Xu W, Chou CJ, Zhang Y. Gao S, et al. Among authors: chou cj. Bioorg Med Chem. 2017 Jun 15;25(12):2981-2994. doi: 10.1016/j.bmc.2017.03.036. Epub 2017 Mar 19. Bioorg Med Chem. 2017. PMID: 28511906 Free PMC article.

9

Class I HDAC Inhibitors Display Different Antitumor Mechanism in Leukemia and Prostatic Cancer Cells Depending on Their p53 Status.

Li X, Peterson YK, Inks ES, Himes RA, Li J, Zhang Y, Kong X, Chou CJ. Li X, et al. Among authors: chou cj. J Med Chem. 2018 Mar 22;61(6):2589-2603. doi: 10.1021/acs.jmedchem.8b00136. Epub 2018 Mar 9. J Med Chem. 2018. PMID: 29499113 Free PMC article.

10

Discovery of meta-sulfamoyl N-hydroxybenzamides as HDAC8 selective inhibitors.

Zhao C, Zang J, Ding Q, Inks ES, Xu W, Chou CJ, Zhang Y. Zhao C, et al. Among authors: chou cj. Eur J Med Chem. 2018 Apr 25;150:282-291. doi: 10.1016/j.ejmech.2018.03.002. Epub 2018 Mar 6. Eur J Med Chem. 2018. PMID: 29533873

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