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ACE2-IgG1 fusions with improved in vitro and in vivo activity against SARS-CoV-2.
Iwanaga N, Cooper L, Rong L, Maness NJ, Beddingfield B, Qin Z, Crabtree J, Tripp RA, Yang H, Blair R, Jangra S, García-Sastre A, Schotsaert M, Chandra S, Robinson JE, Srivastava A, Rabito F, Qin X, Kolls JK. Iwanaga N, et al. Among authors: beddingfield b. iScience. 2022 Jan 21;25(1):103670. doi: 10.1016/j.isci.2021.103670. Epub 2021 Dec 20. iScience. 2022. PMID: 34957381 Free PMC article.
Lung Expression of Human Angiotensin-Converting Enzyme 2 Sensitizes the Mouse to SARS-CoV-2 Infection.
Han K, Blair RV, Iwanaga N, Liu F, Russell-Lodrigue KE, Qin Z, Midkiff CC, Golden NA, Doyle-Meyers LA, Kabir ME, Chandler KE, Cutrera KL, Ren M, Monjure CJ, Lehmicke G, Fischer T, Beddingfield B, Wanek AG, Birnbaum A, Maness NJ, Roy CJ, Datta PK, Rappaport J, Kolls JK, Qin X. Han K, et al. Among authors: beddingfield b. Am J Respir Cell Mol Biol. 2021 Jan;64(1):79-88. doi: 10.1165/rcmb.2020-0354OC. Am J Respir Cell Mol Biol. 2021. PMID: 32991819 Free PMC article.
Effective Prophylaxis of COVID-19 in Rhesus Macaques Using a Combination of Two Parenterally-Administered SARS-CoV-2 Neutralizing Antibodies.
Beddingfield BJ, Maness NJ, Fears AC, Rappaport J, Aye PP, Russell-Lodrigue K, Doyle-Meyers LA, Blair RV, Carias AM, Madden PJ, Redondo RL, Gao H, Montefiori D, Hope TJ, Roy CJ. Beddingfield BJ, et al. Front Cell Infect Microbiol. 2021 Nov 18;11:753444. doi: 10.3389/fcimb.2021.753444. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34869063 Free PMC article.
Acute Respiratory Distress in Aged, SARS-CoV-2-Infected African Green Monkeys but Not Rhesus Macaques.
Blair RV, Vaccari M, Doyle-Meyers LA, Roy CJ, Russell-Lodrigue K, Fahlberg M, Monjure CJ, Beddingfield B, Plante KS, Plante JA, Weaver SC, Qin X, Midkiff CC, Lehmicke G, Golden N, Threeton B, Penney T, Allers C, Barnes MB, Pattison M, Datta PK, Maness NJ, Birnbaum A, Fischer T, Bohm RP, Rappaport J. Blair RV, et al. Among authors: beddingfield b. Am J Pathol. 2021 Feb;191(2):274-282. doi: 10.1016/j.ajpath.2020.10.016. Epub 2020 Nov 7. Am J Pathol. 2021. PMID: 33171111 Free PMC article.
29 results