Flick MJ - Search Results

1

Suppression of fibrin(ogen)-driven pathologies in disease models through controlled knockdown by lipid nanoparticle delivery of siRNA.

Juang LJ, Hur WS, Silva LM, Strilchuk AW, Francisco B, Leung J, Robertson MK, Groeneveld DJ, La Prairie B, Chun EM, Cap AP, Luyendyk JP, Palumbo JS, Cullis PR, Bugge TH, Flick MJ, Kastrup CJ. Juang LJ, et al. Among authors: flick mj. Blood. 2022 Mar 3;139(9):1302-1311. doi: 10.1182/blood.2021014559. Blood. 2022. PMID: 34958662 Free PMC article.

2

The receptor for urokinase-type plasminogen activator is not essential for mouse development or fertility.

Bugge TH, Suh TT, Flick MJ, Daugherty CC, Rømer J, Solberg H, Ellis V, Danø K, Degen JL. Bugge TH, et al. Among authors: flick mj. J Biol Chem. 1995 Jul 14;270(28):16886-94. doi: 10.1074/jbc.270.28.16886. J Biol Chem. 1995. PMID: 7622505 Free article.

3

Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction.

Bugge TH, Flick MJ, Daugherty CC, Degen JL. Bugge TH, et al. Among authors: flick mj. Genes Dev. 1995 Apr 1;9(7):794-807. doi: 10.1101/gad.9.7.794. Genes Dev. 1995. PMID: 7705657 Free article.

4

Urokinase-type plasminogen activator is effective in fibrin clearance in the absence of its receptor or tissue-type plasminogen activator.

Bugge TH, Flick MJ, Danton MJ, Daugherty CC, Romer J, Dano K, Carmeliet P, Collen D, Degen JL. Bugge TH, et al. Among authors: flick mj. Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):5899-904. doi: 10.1073/pnas.93.12.5899. Proc Natl Acad Sci U S A. 1996. PMID: 8650190 Free PMC article.

5

Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation.

Bugge TH, Xiao Q, Kombrinck KW, Flick MJ, Holmbäck K, Danton MJ, Colbert MC, Witte DP, Fujikawa K, Davie EW, Degen JL. Bugge TH, et al. Among authors: flick mj. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6258-63. doi: 10.1073/pnas.93.13.6258. Proc Natl Acad Sci U S A. 1996. PMID: 8692802 Free PMC article.

6

Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency.

Bugge TH, Kombrinck KW, Flick MJ, Daugherty CC, Danton MJ, Degen JL. Bugge TH, et al. Among authors: flick mj. Cell. 1996 Nov 15;87(4):709-19. doi: 10.1016/s0092-8674(00)81390-2. Cell. 1996. PMID: 8929539 Free article.

7

Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice.

Bugge TH, Lund LR, Kombrinck KK, Nielsen BS, Holmbäck K, Drew AF, Flick MJ, Witte DP, Danø K, Degen JL. Bugge TH, et al. Among authors: flick mj. Oncogene. 1998 Jun 18;16(24):3097-104. doi: 10.1038/sj.onc.1201869. Oncogene. 1998. PMID: 9671388

8

Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell-mediated elimination of tumor cells.

Palumbo JS, Talmage KE, Massari JV, La Jeunesse CM, Flick MJ, Kombrinck KW, Jirousková M, Degen JL. Palumbo JS, et al. Among authors: flick mj. Blood. 2005 Jan 1;105(1):178-85. doi: 10.1182/blood-2004-06-2272. Epub 2004 Sep 14. Blood. 2005. PMID: 15367435 Free article.

9

Tumor cell-associated tissue factor and circulating hemostatic factors cooperate to increase metastatic potential through natural killer cell-dependent and-independent mechanisms.

Palumbo JS, Talmage KE, Massari JV, La Jeunesse CM, Flick MJ, Kombrinck KW, Hu Z, Barney KA, Degen JL. Palumbo JS, et al. Among authors: flick mj. Blood. 2007 Jul 1;110(1):133-41. doi: 10.1182/blood-2007-01-065995. Epub 2007 Mar 19. Blood. 2007. PMID: 17371949 Free PMC article.

10

Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin alphaMbeta2 binding motif.

Flick MJ, LaJeunesse CM, Talmage KE, Witte DP, Palumbo JS, Pinkerton MD, Thornton S, Degen JL. Flick MJ, et al. J Clin Invest. 2007 Nov;117(11):3224-35. doi: 10.1172/JCI30134. J Clin Invest. 2007. PMID: 17932565 Free PMC article.

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