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COVID-19 vaccine failure in chronic lymphocytic leukaemia and monoclonal B-lymphocytosis; humoural and cellular immunity.
Shen Y, Freeman JA, Holland J, Solterbeck A, Naidu K, Soosapilla A, Downe P, Tang C, Kerridge I, Wallman L, Van Bilsen N, Milogiannakis V, Akerman A, Martins Costa Gomes G, Sandgren K, Cunningham AL, Turville S, Mulligan SP. Shen Y, et al. Br J Haematol. 2022 Apr;197(1):41-51. doi: 10.1111/bjh.18014. Epub 2022 Jan 5. Br J Haematol. 2022. PMID: 34962656
MEK1/2 inhibition by binimetinib is effective as a single agent and potentiates the actions of Venetoclax and ABT-737 under conditions that mimic the chronic lymphocytic leukaemia (CLL) tumour microenvironment.
Crassini K, Shen Y, Stevenson WS, Christopherson R, Ward C, Mulligan SP, Best OG. Crassini K, et al. Among authors: shen y. Br J Haematol. 2018 Aug;182(3):360-372. doi: 10.1111/bjh.15282. Epub 2018 May 16. Br J Haematol. 2018. PMID: 29767411 Free article.
Therapeutic approaches and drug-resistance in chronic lymphocytic leukaemia.
Fatima N, Crassini KR, Thurgood L, Shen Y, Christopherson RI, Kuss B, Mulligan SP, Best OG. Fatima N, et al. Among authors: shen y. Cancer Drug Resist. 2020 May 11;3(3):532-549. doi: 10.20517/cdr.2019.111. eCollection 2020. Cancer Drug Resist. 2020. PMID: 35582439 Free PMC article. Review.
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