Zarate C - Search Results

1

Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors.

Keylor MH, Gulati A, Kattar SD, Johnson RE, Chau RW, Margrey KA, Ardolino MJ, Zarate C, Poremba KE, Simov V, Morriello GJ, Acton JJ, Pio B, Yan X, Palte RL, McMinn SE, Nogle L, Lesburg CA, Adpressa D, Lin S, Neelamkavil S, Liu P, Su J, Hegde LG, Woodhouse JD, Faltus R, Xiong T, Ciaccio PJ, Piesvaux J, Otte KM, Wood HB, Kennedy ME, Bennett DJ, DiMauro EF, Fell MJ, Fuller PH. Keylor MH, et al. Among authors: zarate c. J Med Chem. 2022 Jan 13;65(1):838-856. doi: 10.1021/acs.jmedchem.1c01968. Epub 2021 Dec 30. J Med Chem. 2022. PMID: 34967623

2

Ni(I)-X Complexes Bearing a Bulky α-Diimine Ligand: Synthesis, Structure, and Superior Catalytic Performance in the Hydrogen Isotope Exchange in Pharmaceuticals.

Zarate C, Yang H, Bezdek MJ, Hesk D, Chirik PJ. Zarate C, et al. J Am Chem Soc. 2019 Mar 27;141(12):5034-5044. doi: 10.1021/jacs.9b00939. Epub 2019 Mar 13. J Am Chem Soc. 2019. PMID: 30827090

3

Benzyltriboronates: Building Blocks for Diastereoselective Carbon-Carbon Bond Formation.

Palmer WN, Zarate C, Chirik PJ. Palmer WN, et al. Among authors: zarate c. J Am Chem Soc. 2017 Feb 22;139(7):2589-2592. doi: 10.1021/jacs.6b12896. Epub 2017 Feb 13. J Am Chem Soc. 2017. PMID: 28156108 Free PMC article.

4

A Mild and Ligand-Free Ni-Catalyzed Silylation via C-OMe Cleavage.

Zarate C, Nakajima M, Martin R. Zarate C, et al. J Am Chem Soc. 2017 Jan 25;139(3):1191-1197. doi: 10.1021/jacs.6b10998. Epub 2017 Jan 12. J Am Chem Soc. 2017. PMID: 28030761

5

A mild Ni/Cu-catalyzed silylation via C-O cleavage.

Zarate C, Martin R. Zarate C, et al. J Am Chem Soc. 2014 Feb 12;136(6):2236-9. doi: 10.1021/ja412107b. Epub 2014 Feb 3. J Am Chem Soc. 2014. PMID: 24476124

6

Ni-Catalyzed Borylation of Aryl Fluorides via C-F Cleavage.

Liu XW, Echavarren J, Zarate C, Martin R. Liu XW, et al. Among authors: zarate c. J Am Chem Soc. 2015 Oct 7;137(39):12470-3. doi: 10.1021/jacs.5b08103. Epub 2015 Sep 25. J Am Chem Soc. 2015. PMID: 26397717

7

Ipso-Borylation of Aryl Ethers via Ni-Catalyzed C-OMe Cleavage.

Zarate C, Manzano R, Martin R. Zarate C, et al. J Am Chem Soc. 2015 Jun 3;137(21):6754-7. doi: 10.1021/jacs.5b03955. Epub 2015 May 22. J Am Chem Soc. 2015. PMID: 25978094

8

A Mild and Direct Site-Selective sp² C-H Silylation of (Poly)Azines.

Gu Y, Shen Y, Zarate C, Martin R. Gu Y, et al. Among authors: zarate c. J Am Chem Soc. 2019 Jan 9;141(1):127-132. doi: 10.1021/jacs.8b12063. Epub 2018 Dec 21. J Am Chem Soc. 2019. PMID: 30562018

9

Metal-catalyzed activation of ethers via C-O bond cleavage: a new strategy for molecular diversity.

Cornella J, Zarate C, Martin R. Cornella J, et al. Among authors: zarate c. Chem Soc Rev. 2014 Dec 7;43(23):8081-97. doi: 10.1039/c4cs00206g. Epub 2014 Aug 26. Chem Soc Rev. 2014. PMID: 25157613

10

Base-Mediated Defluorosilylation of C(sp² )-F and C(sp³ )-F Bonds.

Liu XW, Zarate C, Martin R. Liu XW, et al. Among authors: zarate c. Angew Chem Int Ed Engl. 2019 Feb 11;58(7):2064-2068. doi: 10.1002/anie.201813294. Epub 2019 Jan 17. Angew Chem Int Ed Engl. 2019. PMID: 30575235

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