Zhang N - Search Results

1

Rational design and synthesis of Oreoch-2 analogues as efficient broad-spectrum antimicrobial peptides.

Zhang N, Gu X, Song D, Zhang P, Zhang N, Chen W, Ji S, Qi Y, Ma S. Zhang N, et al. Among authors: zhang p. Bioorg Chem. 2022 Feb;119:105583. doi: 10.1016/j.bioorg.2021.105583. Epub 2021 Dec 24. Bioorg Chem. 2022. PMID: 34971943

2

Design, synthesis and structure-activity relationships of novel N11-, C12- and C13-substituted 15-membered homo-aza-clarithromycin derivatives against various resistant bacteria.

Qin Y, Song D, Teng Y, Liu X, Zhang P, Zhang N, Zhang N, Chen W, Ma S. Qin Y, et al. Among authors: zhang n, zhang p. Bioorg Chem. 2021 Aug;113:104992. doi: 10.1016/j.bioorg.2021.104992. Epub 2021 May 18. Bioorg Chem. 2021. PMID: 34051415

3

Modification of 5-methylphenanthridium from benzothiazoles to indoles as potent FtsZ inhibitors: Broadening the antibacterial spectrum toward vancomycin-resistant enterococci.

Zhang N, Song D, Chen W, Zhang S, Zhang P, Zhang N, Ma S. Zhang N, et al. Among authors: zhang s, zhang p. Eur J Med Chem. 2021 Nov 15;224:113723. doi: 10.1016/j.ejmech.2021.113723. Epub 2021 Jul 26. Eur J Med Chem. 2021. PMID: 34340044

4

Design, synthesis and evaluation of novel 9-arylalkyl-10-methylacridinium derivatives as highly potent FtsZ-targeting antibacterial agents.

Song D, Zhang N, Zhang P, Zhang N, Chen W, Zhang L, Guo T, Gu X, Ma S. Song D, et al. Among authors: zhang n, zhang l, zhang p. Eur J Med Chem. 2021 Oct 5;221:113480. doi: 10.1016/j.ejmech.2021.113480. Epub 2021 Apr 28. Eur J Med Chem. 2021. PMID: 33964649

5

Discovery of 1,3,4-oxadiazol-2-one-containing benzamide derivatives targeting FtsZ as highly potent agents of killing a variety of MDR bacteria strains.

Bi F, Song D, Qin Y, Liu X, Teng Y, Zhang N, Zhang P, Zhang N, Ma S. Bi F, et al. Among authors: zhang n, zhang p. Bioorg Med Chem. 2019 Jul 15;27(14):3179-3193. doi: 10.1016/j.bmc.2019.06.010. Epub 2019 Jun 7. Bioorg Med Chem. 2019. PMID: 31200986

6

Design and structural optimization of novel 2H-benzo[h]chromene derivatives that target AcrB and reverse bacterial multidrug resistance.

Wang Y, Alenazy R, Gu X, Polyak SW, Zhang P, Sykes MJ, Zhang N, Venter H, Ma S. Wang Y, et al. Among authors: zhang n, zhang p. Eur J Med Chem. 2021 Mar 5;213:113049. doi: 10.1016/j.ejmech.2020.113049. Epub 2020 Nov 27. Eur J Med Chem. 2021. PMID: 33279291

7

Research Progress of 70 kDa Ribosomal Protein S6 Kinase (P70S6K) Inhibitors as Effective Therapeutic Tools for Obesity, Type II Diabetes and Cancer.

Zhang N, Ma S. Zhang N, et al. Curr Med Chem. 2020;27(28):4699-4719. doi: 10.2174/0929867327666200114113139. Curr Med Chem. 2020. PMID: 31942845

8

Total Synthesis of Semaglutide Based on a Soluble Hydrophobic-Support-Assisted Liquid-Phase Synthetic Method.

Liu X, Zhang N, Gu X, Qin Y, Song D, Zhang L, Ma S. Liu X, et al. Among authors: zhang n, zhang l. ACS Comb Sci. 2020 Dec 14;22(12):821-825. doi: 10.1021/acscombsci.0c00134. Epub 2020 Oct 15. ACS Comb Sci. 2020. PMID: 33058727

9

Synthesis and biological evaluation of antibacterial activity of novel clarithromycin derivatives incorporating 1,2,3-triazole moieties at the 4''- and 11-OH positions.

Qin Y, Sun M, Zhang N, Yang Y, Ma P. Qin Y, et al. Among authors: zhang n. Bioorg Chem. 2022 Oct;127:106020. doi: 10.1016/j.bioorg.2022.106020. Epub 2022 Jul 9. Bioorg Chem. 2022. PMID: 35841669

10

Structure-activity relationship and biological evaluation of 12 N-substituted aloperine derivatives as PD-L1 down-regulatory agents through proteasome pathway.

Zeng QX, Wang K, Zhang X, Shi YL, Dou YY, Guo ZH, Zhang XT, Zhang N, Deng HB, Li YH, Song DQ. Zeng QX, et al. Among authors: zhang n, zhang xt, zhang x. Bioorg Chem. 2021 Dec;117:105432. doi: 10.1016/j.bioorg.2021.105432. Epub 2021 Oct 16. Bioorg Chem. 2021. PMID: 34678602

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