D'Angelo I - Search Results

1

Development of a potent high-affinity human therapeutic antibody via novel application of recombination signal sequence-based affinity maturation.

Kielczewska A, D'Angelo I, Amador MS, Wang T, Sudom A, Min X, Rathanaswami P, Pigott C, Foltz IN. Kielczewska A, et al. J Biol Chem. 2022 Feb;298(2):101533. doi: 10.1016/j.jbc.2021.101533. Epub 2021 Dec 29. J Biol Chem. 2022. PMID: 34973336 Free PMC article.

2

A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism.

Dresen C, Lin LY, D'Angelo I, Tocheva EI, Strynadka N, Eltis LD. Dresen C, et al. J Biol Chem. 2010 Jul 16;285(29):22264-75. doi: 10.1074/jbc.M109.099028. Epub 2010 May 6. J Biol Chem. 2010. PMID: 20448045 Free PMC article.

3

Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis.

Capyk JK, D'Angelo I, Strynadka NC, Eltis LD. Capyk JK, et al. J Biol Chem. 2009 Apr 10;284(15):9937-46. doi: 10.1074/jbc.M900719200. Epub 2009 Feb 20. J Biol Chem. 2009. PMID: 19234303 Free PMC article.

4

Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis.

Yam KC, D'Angelo I, Kalscheuer R, Zhu H, Wang JX, Snieckus V, Ly LH, Converse PJ, Jacobs WR Jr, Strynadka N, Eltis LD. Yam KC, et al. PLoS Pathog. 2009 Mar;5(3):e1000344. doi: 10.1371/journal.ppat.1000344. Epub 2009 Mar 20. PLoS Pathog. 2009. PMID: 19300498 Free PMC article.

5

Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase.

Ludwiczek ML, D'Angelo I, Yalloway GN, Brockerman JA, Okon M, Nielsen JE, Strynadka NC, Withers SG, McIntosh LP. Ludwiczek ML, et al. Biochemistry. 2013 May 7;52(18):3138-56. doi: 10.1021/bi400034m. Epub 2013 Apr 24. Biochemistry. 2013. PMID: 23578322

6

Circular permutation of Bacillus circulans xylanase: a kinetic and structural study.

Reitinger S, Yu Y, Wicki J, Ludwiczek M, D'Angelo I, Baturin S, Okon M, Strynadka NC, Lutz S, Withers SG, McIntosh LP. Reitinger S, et al. Biochemistry. 2010 Mar 23;49(11):2464-74. doi: 10.1021/bi100036f. Biochemistry. 2010. PMID: 20163191

7

AlbuCORE: an albumin-based molecular scaffold for multivalent biologics design.

Sanches M, D'Angelo I, Jaramillo M, Baardsnes J, Zwaagstra J, Schrag J, Schoenhofen I, Acchione M, Lawn S, Wickman G, Weisser N, Poon DKY, Ng G, Dixit S. Sanches M, et al. MAbs. 2020 Jan-Dec;12(1):1802188. doi: 10.1080/19420862.2020.1802188. MAbs. 2020. PMID: 32816577 Free PMC article.

8

Benchmarking immunoinformatic tools for the analysis of antibody repertoire sequences.

Smakaj E, Babrak L, Ohlin M, Shugay M, Briney B, Tosoni D, Galli C, Grobelsek V, D'Angelo I, Olson B, Reddy S, Greiff V, Trück J, Marquez S, Lees W, Miho E. Smakaj E, et al. Bioinformatics. 2020 Mar 1;36(6):1731-1739. doi: 10.1093/bioinformatics/btz845. Bioinformatics. 2020. PMID: 31873728 Free PMC article.

9

Improving biophysical properties of a bispecific antibody scaffold to aid developability: quality by molecular design.

Von Kreudenstein TS, Escobar-Carbrera E, Lario PI, D'Angelo I, Brault K, Kelly J, Durocher Y, Baardsnes J, Woods RJ, Xie MH, Girod PA, Suits MD, Boulanger MJ, Poon DK, Ng GY, Dixit SB. Von Kreudenstein TS, et al. MAbs. 2013 Sep-Oct;5(5):646-54. doi: 10.4161/mabs.25632. Epub 2013 Jul 8. MAbs. 2013. PMID: 23924797 Free PMC article.

10

Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasis.

Garavaglia S, D'Angelo I, Emanuelli M, Carnevali F, Pierella F, Magni G, Rizzi M. Garavaglia S, et al. J Biol Chem. 2002 Mar 8;277(10):8524-30. doi: 10.1074/jbc.M111589200. Epub 2001 Dec 19. J Biol Chem. 2002. PMID: 11751893 Free article.

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