Covey DF - Search Results

1

Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites.

Dietzen NM, Arcario MJ, Chen LJ, Petroff JT 2nd, Moreland KT, Krishnan K, Brannigan G, Covey DF, Cheng WW. Dietzen NM, et al. Among authors: covey df. Elife. 2022 Jan 4;11:e74306. doi: 10.7554/eLife.74306. Elife. 2022. PMID: 34982031 Free PMC article.

2

New evidence that both T-type calcium channels and GABAA channels are responsible for the potent peripheral analgesic effects of 5alpha-reduced neuroactive steroids.

Pathirathna S, Brimelow BC, Jagodic MM, Krishnan K, Jiang X, Zorumski CF, Mennerick S, Covey DF, Todorovic SM, Jevtovic-Todorovic V. Pathirathna S, et al. Among authors: covey df. Pain. 2005 Apr;114(3):429-443. doi: 10.1016/j.pain.2005.01.009. Pain. 2005. PMID: 15777868

3

Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens.

Katona BW, Krishnan K, Cai ZY, Manion BD, Benz A, Taylor A, Evers AS, Zorumski CF, Mennerick S, Covey DF. Katona BW, et al. Among authors: covey df. Eur J Med Chem. 2008 Jan;43(1):107-13. doi: 10.1016/j.ejmech.2007.02.017. Epub 2007 Mar 12. Eur J Med Chem. 2008. PMID: 17434649

4

GABAergic neurosteroids mediate the effects of ethanol on long-term potentiation in rat hippocampal slices.

Izumi Y, Murayama K, Tokuda K, Krishnan K, Covey DF, Zorumski CF. Izumi Y, et al. Among authors: covey df. Eur J Neurosci. 2007 Oct;26(7):1881-8. doi: 10.1111/j.1460-9568.2007.05809.x. Epub 2007 Sep 20. Eur J Neurosci. 2007. PMID: 17883414

5

Neurosteroid analogues. 14. Alternative ring system scaffolds: GABA modulatory and anesthetic actions of cyclopenta[b]phenanthrenes and cyclopenta[b]anthracenes.

Scaglione JB, Jastrzebska I, Krishnan K, Li P, Akk G, Manion BD, Benz A, Taylor A, Rath NP, Evers AS, Zorumski CF, Mennerick S, Covey DF. Scaglione JB, et al. Among authors: covey df. J Med Chem. 2008 Mar 13;51(5):1309-18. doi: 10.1021/jm701128r. Epub 2008 Feb 15. J Med Chem. 2008. PMID: 18275132

6

Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions.

Gale SE, Westover EJ, Dudley N, Krishnan K, Merlin S, Scherrer DE, Han X, Zhai X, Brockman HL, Brown RE, Covey DF, Schaffer JE, Schlesinger P, Ory DS. Gale SE, et al. Among authors: covey df. J Biol Chem. 2009 Jan 16;284(3):1755-64. doi: 10.1074/jbc.M807210200. Epub 2008 Nov 6. J Biol Chem. 2009. PMID: 18996837 Free PMC article.

7

Synthesis of 19-Trideuterated ent-Testosterone and the GABA(A) Receptor Potentiators ent-Androsterone and ent-Etiocholanolone.

Komarapuri S, Krishnan K, Covey DF. Komarapuri S, et al. Among authors: covey df. J Labelled Comp Radiopharm. 2008 Nov;51(14):430-434. doi: 10.1002/jlcr.1558. J Labelled Comp Radiopharm. 2008. PMID: 19122784 Free PMC article.

8

The influence of neuroactive steroid lipophilicity on GABAA receptor modulation: evidence for a low-affinity interaction.

Chisari M, Eisenman LN, Krishnan K, Bandyopadhyaya AK, Wang C, Taylor A, Benz A, Covey DF, Zorumski CF, Mennerick S. Chisari M, et al. Among authors: covey df. J Neurophysiol. 2009 Aug;102(2):1254-64. doi: 10.1152/jn.00346.2009. Epub 2009 Jun 24. J Neurophysiol. 2009. PMID: 19553485 Free PMC article.

9

Photodynamic effects of steroid-conjugated fluorophores on GABAA receptors.

Shu HJ, Eisenman LN, Wang C, Bandyopadhyaya AK, Krishnan K, Taylor A, Benz AM, Manion B, Evers AS, Covey DF, Zorumski CF, Mennerick S. Shu HJ, et al. Among authors: covey df. Mol Pharmacol. 2009 Oct;76(4):754-65. doi: 10.1124/mol.109.057687. Epub 2009 Jul 13. Mol Pharmacol. 2009. PMID: 19596835 Free PMC article.

10

Neurosteroid analogues. 16. A new explanation for the lack of anesthetic effects of δ(16)-alphaxalone and identification of a δ(17(20)) analogue with potent anesthetic activity.

Stastna E, Krishnan K, Manion BD, Taylor A, Rath NP, Chen ZW, Evers AS, Zorumski CF, Mennerick S, Covey DF. Stastna E, et al. Among authors: covey df. J Med Chem. 2011 Jun 9;54(11):3926-34. doi: 10.1021/jm2002487. Epub 2011 May 6. J Med Chem. 2011. PMID: 21504158 Free PMC article.

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