Okamoto H - Search Results

1

Glutaminase 2 knockdown reduces hyperammonemia and associated lethality of urea cycle disorder mouse model.

Mao X, Chen H, Lin AZ, Kim S, Burczynski ME, Na E, Halasz G, Sleeman MW, Murphy AJ, Okamoto H, Cheng X. Mao X, et al. Among authors: okamoto h. J Inherit Metab Dis. 2022 May;45(3):470-480. doi: 10.1002/jimd.12474. Epub 2022 Feb 4. J Inherit Metab Dis. 2022. PMID: 34988999 Free PMC article.

2

Genetic deletion of Trb3, the mammalian Drosophila tribbles homolog, displays normal hepatic insulin signaling and glucose homeostasis.

Okamoto H, Latres E, Liu R, Thabet K, Murphy A, Valenzeula D, Yancopoulos GD, Stitt TN, Glass DJ, Sleeman MW. Okamoto H, et al. Diabetes. 2007 May;56(5):1350-6. doi: 10.2337/db06-1448. Epub 2007 Feb 15. Diabetes. 2007. PMID: 17303803

3

Peptide YY regulates bone turnover in rodents.

Wortley KE, Garcia K, Okamoto H, Thabet K, Anderson KD, Shen V, Herman JP, Valenzuela D, Yancopoulos GD, Tschöp MH, Murphy A, Sleeman MW. Wortley KE, et al. Among authors: okamoto h. Gastroenterology. 2007 Nov;133(5):1534-43. doi: 10.1053/j.gastro.2007.08.024. Epub 2007 Aug 15. Gastroenterology. 2007. PMID: 17920065

4

Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditure.

Watson E, Fargali S, Okamoto H, Sadahiro M, Gordon RE, Chakraborty T, Sleeman MW, Salton SR. Watson E, et al. Among authors: okamoto h. BMC Physiol. 2009 Oct 28;9:19. doi: 10.1186/1472-6793-9-19. BMC Physiol. 2009. PMID: 19863797 Free PMC article.

5

Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys.

Okamoto H, Kim J, Aglione J, Lee J, Cavino K, Na E, Rafique A, Kim JH, Harp J, Valenzuela DM, Yancopoulos GD, Murphy AJ, Gromada J. Okamoto H, et al. Endocrinology. 2015 Aug;156(8):2781-94. doi: 10.1210/en.2015-1011. Epub 2015 May 28. Endocrinology. 2015. PMID: 26020795

6

Loss of SFRP4 Alters Body Size, Food Intake, and Energy Expenditure in Diet-Induced Obese Male Mice.

Mastaitis J, Eckersdorff M, Min S, Xin Y, Cavino K, Aglione J, Okamoto H, Na E, Stitt T, Dominguez MG, Schmahl JP, Lin C, Gale NW, Valenzuela DM, Murphy AJ, Yancopoulos GD, Gromada J. Mastaitis J, et al. Among authors: okamoto h. Endocrinology. 2015 Dec;156(12):4502-10. doi: 10.1210/en.2015-1257. Epub 2015 Sep 25. Endocrinology. 2015. PMID: 26406932

7

Use of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells.

Xin Y, Kim J, Ni M, Wei Y, Okamoto H, Lee J, Adler C, Cavino K, Murphy AJ, Yancopoulos GD, Lin HC, Gromada J. Xin Y, et al. Among authors: okamoto h. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3293-8. doi: 10.1073/pnas.1602306113. Epub 2016 Mar 7. Proc Natl Acad Sci U S A. 2016. PMID: 26951663 Free PMC article.

8

Single-Cell RNAseq Reveals That Pancreatic β-Cells From Very Old Male Mice Have a Young Gene Signature.

Xin Y, Okamoto H, Kim J, Ni M, Adler C, Cavino K, Na E, Murphy AJ, Yancopoulos GD, Lin C, Gromada J. Xin Y, et al. Among authors: okamoto h. Endocrinology. 2016 Sep;157(9):3431-8. doi: 10.1210/en.2016-1235. Epub 2016 Jul 28. Endocrinology. 2016. PMID: 27466694

9

RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes.

Xin Y, Kim J, Okamoto H, Ni M, Wei Y, Adler C, Murphy AJ, Yancopoulos GD, Lin C, Gromada J. Xin Y, et al. Among authors: okamoto h. Cell Metab. 2016 Oct 11;24(4):608-615. doi: 10.1016/j.cmet.2016.08.018. Epub 2016 Sep 22. Cell Metab. 2016. PMID: 27667665 Free article.

10

Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice.

Okamoto H, Cavino K, Na E, Krumm E, Kim SY, Cheng X, Murphy AJ, Yancopoulos GD, Gromada J. Okamoto H, et al. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2753-2758. doi: 10.1073/pnas.1621069114. Epub 2017 Jan 23. Proc Natl Acad Sci U S A. 2017. PMID: 28115707 Free PMC article.

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