Brown AN - Search Results

1

New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo.

Thorpe PE, Wallace PM, Knowles PP, Relf MG, Brown AN, Watson GJ, Knyba RE, Wawrzynczak EJ, Blakey DC. Thorpe PE, et al. Among authors: brown an. Cancer Res. 1987 Nov 15;47(22):5924-31. Cancer Res. 1987. PMID: 3499221

2

Evaluation of ricin A chain-containing immunotoxins directed against CD19 and CD22 antigens on normal and malignant human B-cells as potential reagents for in vivo therapy.

Ghetie MA, May RD, Till M, Uhr JW, Ghetie V, Knowles PP, Relf M, Brown A, Wallace PM, Janossy G, et al. Ghetie MA, et al. Cancer Res. 1988 May 1;48(9):2610-7. Cancer Res. 1988. PMID: 2451562 Clinical Trial.

3

Comparison of two anti-Thy 1.1-abrin A-chain immunotoxins prepared with different cross-linking agents: antitumor effects, in vivo fate, and tumor cell mutants.

Thorpe PE, Blakey DC, Brown AN, Knowles PP, Knyba RE, Wallace PM, Watson GJ, Wawrzynczak EJ. Thorpe PE, et al. Among authors: brown an. J Natl Cancer Inst. 1987 Nov;79(5):1101-12. J Natl Cancer Inst. 1987. PMID: 2890786

4

Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A-chain and hindered disulfide linkages.

Thorpe PE, Wallace PM, Knowles PP, Relf MG, Brown AN, Watson GJ, Blakey DC, Newell DR. Thorpe PE, et al. Among authors: brown an. Cancer Res. 1988 Nov 15;48(22):6396-403. Cancer Res. 1988. PMID: 3263186

5

Resistance of myeloid leukaemia cell lines to ricin A-chain immunotoxins.

Engert A, Brown A, Thorpe P. Engert A, et al. Leuk Res. 1991;15(11):1079-86. doi: 10.1016/0145-2126(91)90115-a. Leuk Res. 1991. PMID: 1961012

6

Evaluation of four CD22 antibodies as ricin A chain-containing immunotoxins for the in vivo therapy of human B-cell leukemias and lymphomas.

Shen GL, Li JL, Ghetie MA, Ghetie V, May RD, Till M, Brown AN, Relf M, Knowles P, Uhr JW, et al. Shen GL, et al. Among authors: brown an. Int J Cancer. 1988 Nov 15;42(5):792-7. doi: 10.1002/ijc.2910420527. Int J Cancer. 1988. PMID: 3263328

7

Selective cytotoxic activity of immunotoxins composed of a monoclonal anti-Thy 1.1 antibody and the ribosome-inactivating proteins bryodin and momordin.

Stirpe F, Wawrzynczak EJ, Brown AN, Knyba RE, Watson GJ, Barbieri L, Thorpe PE. Stirpe F, et al. Among authors: brown an. Br J Cancer. 1988 Nov;58(5):558-61. doi: 10.1038/bjc.1988.258. Br J Cancer. 1988. PMID: 3265330 Free PMC article.

8

The preparation of deglycosylated ricin by recombination of glycosidase-treated A- and B-chains: effects of deglycosylation on toxicity and in vivo distribution.

Foxwell BM, Blakey DC, Brown AN, Donovan TA, Thorpe PE. Foxwell BM, et al. Among authors: brown an. Biochim Biophys Acta. 1987 Jan 20;923(1):59-65. doi: 10.1016/0304-4165(87)90126-7. Biochim Biophys Acta. 1987. PMID: 3099852

9

An immunotoxin composed of monoclonal anti-Thy 1.1 antibody and a ribosome-inactivating protein from Saponaria officinalis: potent antitumor effects in vitro and in vivo.

Thorpe PE, Brown AN, Bremner JA Jr, Foxwell BM, Stirpe F. Thorpe PE, et al. Among authors: brown an. J Natl Cancer Inst. 1985 Jul;75(1):151-9. J Natl Cancer Inst. 1985. PMID: 3859688

10

Hepatotoxicity of immunotoxins made with saporin, a ribosome-inactivating protein from Saponaria officinalis.

Stirpe F, Derenzini M, Barbieri L, Farabegoli F, Brown AN, Knowles PP, Thorpe PE. Stirpe F, et al. Among authors: brown an. Virchows Arch B Cell Pathol Incl Mol Pathol. 1987;53(5):259-71. doi: 10.1007/BF02890252. Virchows Arch B Cell Pathol Incl Mol Pathol. 1987. PMID: 2889289

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