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Feeding Brassica vegetables to rats leads to the formation of characteristic DNA adducts (from 1-methoxy-3-indolylmethyl glucosinolate) in many tissues.
Arch Toxicol. 2022 Mar;96(3):933-944. doi: 10.1007/s00204-021-03216-8. Epub 2022 Jan 7.
Arch Toxicol. 2022.
PMID: 34997255
Free PMC article.
1-Methoxy-3-indolylmethyl glucosinolate; a potent genotoxicant in bacterial and mammalian cells: Mechanisms of bioactivation.
Glatt H, Baasanjav-Gerber C, Schumacher F, Monien BH, Schreiner M, Frank H, Seidel A, Engst W.
Glatt H, et al. Among authors: baasanjav gerber c.
Chem Biol Interact. 2011 Jun 30;192(1-2):81-6. doi: 10.1016/j.cbi.2010.09.009. Epub 2010 Sep 21.
Chem Biol Interact. 2011.
PMID: 20846518
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Identification of glucosinolate congeners able to form DNA adducts and to induce mutations upon activation by myrosinase.
Baasanjav-Gerber C, Monien BH, Mewis I, Schreiner M, Barillari J, Iori R, Glatt H.
Baasanjav-Gerber C, et al.
Mol Nutr Food Res. 2011 May;55(5):783-92. doi: 10.1002/mnfr.201000352. Epub 2011 Jan 7.
Mol Nutr Food Res. 2011.
PMID: 21213326
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Detection of genotoxicants in Brassicales using endogenous DNA as a surrogate target and adducts determined by 32P-postlabelling as an experimental end point.
Baasanjav-Gerber C, Hollnagel HM, Brauchmann J, Iori R, Glatt H.
Baasanjav-Gerber C, et al.
Mutagenesis. 2011 May;26(3):407-13. doi: 10.1093/mutage/geq108. Epub 2010 Dec 30.
Mutagenesis. 2011.
PMID: 21193518
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