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SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display.
Ehling RA, Weber CR, Mason DM, Friedensohn S, Wagner B, Bieberich F, Kapetanovic E, Vazquez-Lombardi R, Di Roberto RB, Hong KL, Wagner C, Pataia M, Overath MD, Sheward DJ, Murrell B, Yermanos A, Cuny AP, Savic M, Rudolf F, Reddy ST. Ehling RA, et al. Among authors: overath md. Cell Rep. 2022 Jan 18;38(3):110242. doi: 10.1016/j.celrep.2021.110242. Epub 2021 Dec 22. Cell Rep. 2022. PMID: 34998467 Free PMC article.
De novo designed proteins neutralize lethal snake venom toxins.
Vázquez Torres S, Benard Valle M, Mackessy SP, Menzies SK, Casewell NR, Ahmadi S, Burlet NJ, Muratspahić E, Sappington I, Overath MD, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera AK, Kang A, Brackenbrough E, Cardoso IA, Crittenden EP, Edge RJ, Decarreau J, Ragotte RJ, Pillai AS, Abedi M, Han HL, Gerben SR, Murray A, Skotheim R, Stuart L, Stewart L, Fryer TJA, Jenkins TP, Baker D. Vázquez Torres S, et al. Among authors: overath md. Nature. 2025 Jan 15. doi: 10.1038/s41586-024-08393-x. Online ahead of print. Nature. 2025. PMID: 39814879
V-ToCs (Venom Toxin Clustering): A tool for the investigation of sequence and structure similarities in snake venom toxins.
Kalogeropoulos K, Rosca V, O'Brien C, Christensen CR, Grahadi R, Sørensen CV, Overath MD, Espi DR, Jenkins DE, Keller UAD, Laustsen AH, Fryer TJ, Jenkins TP. Kalogeropoulos K, et al. Among authors: overath md. Toxicon. 2024 Nov 6;250:108088. doi: 10.1016/j.toxicon.2024.108088. Epub 2024 Aug 31. Toxicon. 2024. PMID: 39222754 Free article.
De novo designed proteins neutralize lethal snake venom toxins.
Torres SV, Valle MB, Mackessy SP, Menzies SK, Casewell NR, Ahmadi S, Burlet NJ, Muratspahić E, Sappington I, Overath MD, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera AK, Kang A, Brackenbrough E, Cardoso IA, Crittenden EP, Edge RJ, Decarreau J, Ragotte RJ, Pillai AS, Abedi M, Han HL, Gerben SR, Murray A, Skotheim R, Stuart L, Stewart L, Fryer TJA, Jenkins TP, Baker D. Torres SV, et al. Among authors: overath md. Res Sq [Preprint]. 2024 May 17:rs.3.rs-4402792. doi: 10.21203/rs.3.rs-4402792/v1. Res Sq. 2024. Update in: Nature. 2025 Jan 15. doi: 10.1038/s41586-024-08393-x PMID: 38798548 Free PMC article. Updated. Preprint.