Porosk L - Search Results

1

Amyloid-like Self-Assembly of a Hydrophobic Cell-Penetrating Peptide and Its Use as a Carrier for Nucleic Acids.

de Mello LR, Porosk L, Lourenço TC, Garcia BBM, Costa CAR, Han SW, de Souza JS, Langel Ü, da Silva ER. de Mello LR, et al. Among authors: porosk l. ACS Appl Bio Mater. 2021 Aug 16;4(8):6404-6416. doi: 10.1021/acsabm.1c00601. Epub 2021 Aug 4. ACS Appl Bio Mater. 2021. PMID: 35006917

2

Approaches for the discovery of new cell-penetrating peptides.

Porosk L, Gaidutšik I, Langel Ü. Porosk L, et al. Expert Opin Drug Discov. 2021 May;16(5):553-565. doi: 10.1080/17460441.2021.1851187. Epub 2020 Dec 1. Expert Opin Drug Discov. 2021. PMID: 33874824 Review.

3

Cell-Penetrating Peptides Predicted From CASC3, AKIP1, and AHRR Proteins.

Porosk L, Põhako K, Arukuusk P, Langel Ü. Porosk L, et al. Front Pharmacol. 2021 Aug 24;12:716226. doi: 10.3389/fphar.2021.716226. eCollection 2021. Front Pharmacol. 2021. PMID: 34504427 Free PMC article.

4

Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models.

Kiisholts K, Kurrikoff K, Arukuusk P, Porosk L, Peters M, Salumets A, Langel Ü. Kiisholts K, et al. Among authors: porosk l. Pharmaceutics. 2021 Oct 5;13(10):1618. doi: 10.3390/pharmaceutics13101618. Pharmaceutics. 2021. PMID: 34683911 Free PMC article.

5

Enhancement of siRNA transfection by the optimization of fatty acid length and histidine content in the CPP.

Porosk L , Arukuusk P , Põhako K , Kurrikoff K , Kiisholts K , Padari K , Pooga M , Langel Ü . Porosk L , et al. Biomater Sci. 2019 Sep 24;7(10):4363-4374. doi: 10.1039/c9bm00688e. Biomater Sci. 2019. PMID: 31411219

6

Endpoint and Kinetic Approaches for Assessing Transfection Efficacy in Mammalian Cell Culture.

Porosk L, Nebogatova J, Gaidutšik I, Langel Ü. Porosk L, et al. Methods Mol Biol. 2022;2383:529-545. doi: 10.1007/978-1-0716-1752-6_33. Methods Mol Biol. 2022. PMID: 34766311

7

Tumor gene therapy by systemic delivery of plasmid DNA with cell-penetrating peptides.

Künnapuu K, Veiman KL, Porosk L, Rammul E, Kiisholts K, Langel Ü, Kurrikoff K. Künnapuu K, et al. Among authors: porosk l. FASEB Bioadv. 2018 Nov 26;1(2):105-114. doi: 10.1096/fba.1026. eCollection 2019 Feb. FASEB Bioadv. 2018. PMID: 32123824 Free PMC article.

8

Predicting Transiently Expressed Protein Yields: Comparison of Transfection Methods in CHO and HEK293.

Porosk L, Nebogatova J, Härk HH, Vunk B, Arukuusk P, Toots U, Ustav M, Langel Ü, Kurrikoff K. Porosk L, et al. Pharmaceutics. 2022 Sep 14;14(9):1949. doi: 10.3390/pharmaceutics14091949. Pharmaceutics. 2022. PMID: 36145697 Free PMC article.

9

Characterization of Peptide-Oligonucleotide Complexes Using Electron Microscopy, Dynamic Light Scattering, and Protease Resistance Assay.

Padari K, Porosk L, Arukuusk P, Pooga M. Padari K, et al. Among authors: porosk l. Methods Mol Biol. 2019;2036:127-139. doi: 10.1007/978-1-4939-9670-4_7. Methods Mol Biol. 2019. PMID: 31410794

10

Supplementation with ions enhances the efficiency of nucleic acid delivery with cell-penetrating peptides.

Gümüşoğlu İI, Maloverjan M, Porosk L, Pooga M. Gümüşoğlu İI, et al. Among authors: porosk l. Biochim Biophys Acta Gen Subj. 2024 Dec;1868(12):130719. doi: 10.1016/j.bbagen.2024.130719. Epub 2024 Oct 5. Biochim Biophys Acta Gen Subj. 2024. PMID: 39369860

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