Leek M - Search Results

1

Targeting the Fusion Process of SARS-CoV-2 Infection by Small Molecule Inhibitors.

Park SB, Irvin P, Hu Z, Khan M, Hu X, Zeng Q, Chen C, Xu M, Leek M, Zang R, Case JB, Zheng W, Ding S, Liang TJ. Park SB, et al. Among authors: leek m. mBio. 2022 Feb 22;13(1):e0323821. doi: 10.1128/mbio.03238-21. Epub 2022 Jan 11. mBio. 2022. PMID: 35012356 Free PMC article.

2

Discovery and Optimization of a 4-Aminopiperidine Scaffold for Inhibition of Hepatitis C Virus Assembly.

Rolt A, Talley DC, Park SB, Hu Z, Dulcey A, Ma C, Irvin P, Leek M, Wang AQ, Stachulski AV, Xu X, Southall N, Ferrer M, Liang TJ, Marugan JJ. Rolt A, et al. Among authors: leek m. J Med Chem. 2021 Jul 8;64(13):9431-9443. doi: 10.1021/acs.jmedchem.1c00696. Epub 2021 Jun 29. J Med Chem. 2021. PMID: 34184537 Free PMC article.

3

Discovery of Small Molecule Entry Inhibitors Targeting the Fusion Peptide of SARS-CoV-2 Spike Protein.

Hu X, Chen CZ, Xu M, Hu Z, Guo H, Itkin Z, Shinn P, Ivin P, Leek M, Liang TJ, Shen M, Zheng W, Hall MD. Hu X, et al. Among authors: leek m. ACS Med Chem Lett. 2021 Jul 28;12(8):1267-1274. doi: 10.1021/acsmedchemlett.1c00263. eCollection 2021 Aug 12. ACS Med Chem Lett. 2021. PMID: 34394844 Free PMC article.

4

A dual conditional CRISPR-Cas9 system to activate gene editing and reduce off-target effects in human stem cells.

Park SB, Uchida T, Tilson S, Hu Z, Ma CD, Leek M, Eichner M, Hong SG, Liang TJ. Park SB, et al. Among authors: leek m. Mol Ther Nucleic Acids. 2022 Apr 27;28:656-669. doi: 10.1016/j.omtn.2022.04.013. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35615005 Free PMC article.

5

SARS-CoV-2 omicron variants harbor spike protein mutations responsible for their attenuated fusogenic phenotype.

Park SB, Khan M, Chiliveri SC, Hu X, Irvin P, Leek M, Grieshaber A, Hu Z, Jang ES, Bax A, Liang TJ. Park SB, et al. Among authors: leek m. Commun Biol. 2023 May 24;6(1):556. doi: 10.1038/s42003-023-04923-x. Commun Biol. 2023. PMID: 37225764 Free PMC article.

6

Repurposing of lonafarnib as a treatment for SARS-CoV-2 infection.

Khan M, Irvin P, Park SB, Ivester HM, Ricardo-Lax I, Leek M, Grieshaber A, Jang ES, Coutermarsh-Ott SL, Zhang Q, Maio N, Jiang JK, Li B, Huang W, Wang AQ, Xu X, Hu Z, Zheng W, Ye Y, Rouault T, Rice CM, Allen IC, Liang TJ. Khan M, et al. Among authors: leek m. JCI Insight. 2024 Dec 3:e182704. doi: 10.1172/jci.insight.182704. Online ahead of print. JCI Insight. 2024. PMID: 39625789 Free article.

7

Additive effects of mild head trauma, blast exposure, and aging within white matter tracts: A novel Diffusion Tensor Imaging analysis approach.

Poliva O, Herrera C, Sugai K, Whittle N, Leek MR, Barnes S, Holshouser B, Yi A, Venezia JH. Poliva O, et al. Among authors: leek mr. J Neuropathol Exp Neurol. 2024 Oct 1;83(10):853-869. doi: 10.1093/jnen/nlae069. J Neuropathol Exp Neurol. 2024. PMID: 39053000

8

Cortical networks for recognition of speech with simultaneous talkers.

Herrera C, Whittle N, Leek MR, Brodbeck C, Lee G, Barcenas C, Barnes S, Holshouser B, Yi A, Venezia JH. Herrera C, et al. Among authors: leek mr. Hear Res. 2023 Sep 15;437:108856. doi: 10.1016/j.heares.2023.108856. Epub 2023 Jul 24. Hear Res. 2023. PMID: 37531847

9

A Phase I Trial of Allogeneic γδ T Lymphocytes From Haploidentical Donors in Patients With Refractory or Relapsed Acute Myeloid Leukemia.

Vydra J, Cosimo E, Lesný P, Wanless RS, Anderson J, Clark AG, Scott A, Nicholson EK, Leek M. Vydra J, et al. Among authors: leek m. Clin Lymphoma Myeloma Leuk. 2023 May;23(5):e232-e239. doi: 10.1016/j.clml.2023.02.003. Epub 2023 Feb 11. Clin Lymphoma Myeloma Leuk. 2023. PMID: 36863897 Free PMC article. Clinical Trial.

10

Task-modulated Sensitivity to Vocal Pitch in the Dorsal Premotor Cortex during Multitalker Speech Recognition.

Venezia JH, Herrera C, Whittle N, Leek MR, Barnes S, Holshouser B, Yi A. Venezia JH, et al. Among authors: leek mr. J Cogn Neurosci. 2022 Oct 1;34(11):2189-2214. doi: 10.1162/jocn_a_01907. J Cogn Neurosci. 2022. PMID: 36007073

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