Lou C - Search Results

1

Chirality transmission in macromolecular domains.

Pandey S, Mandal S, Danielsen MB, Brown A, Hu C, Christensen NJ, Kulakova AV, Song S, Brown T, Jensen KJ, Wengel J, Lou C, Mao H. Pandey S, et al. Among authors: lou c. Nat Commun. 2022 Jan 10;13(1):76. doi: 10.1038/s41467-021-27708-4. Nat Commun. 2022. PMID: 35013247 Free PMC article.

2

2'-Aminoethoxy-2-amino-3-methylpyridine in triplex-forming oligonucleotides: high affinity, selectivity and resistance to enzymatic degradation.

Lou C, Shelbourne M, Fox KR, Brown T. Lou C, et al. Chemistry. 2011 Dec 23;17(52):14851-6. doi: 10.1002/chem.201102287. Epub 2011 Nov 30. Chemistry. 2011. PMID: 22127905

3

Oligonucleotides containing a piperazino-modified 2'-amino-LNA monomer exhibit very high duplex stability and remarkable nuclease resistance.

Lou C, Vester B, Wengel J. Lou C, et al. Chem Commun (Camb). 2015 Mar 7;51(19):4024-7. doi: 10.1039/c5cc00322a. Chem Commun (Camb). 2015. PMID: 25659978 Free article.

4

Peptide-oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic.

Lou C, Martos-Maldonado MC, Madsen CS, Thomsen RP, Midtgaard SR, Christensen NJ, Kjems J, Thulstrup PW, Wengel J, Jensen KJ. Lou C, et al. Nat Commun. 2016 Jul 28;7:12294. doi: 10.1038/ncomms12294. Nat Commun. 2016. PMID: 27464951 Free PMC article.

5

Synthesis and Biophysical Investigations of Oligonucleotides Containing Galactose-Modified DNA, LNA, and 2'-Amino-LNA Monomers.

Ries A, Kumar R, Lou C, Kosbar T, Vengut-Climent E, Jørgensen PT, Morales JC, Wengel J. Ries A, et al. Among authors: lou c. J Org Chem. 2016 Nov 18;81(22):10845-10856. doi: 10.1021/acs.joc.6b01917. Epub 2016 Oct 25. J Org Chem. 2016. PMID: 27736097

6

Oligonucleotides Containing Aminated 2'-Amino-LNA Nucleotides: Synthesis and Strong Binding to Complementary DNA and RNA.

Lou C, Samuelsen SV, Christensen NJ, Vester B, Wengel J. Lou C, et al. Bioconjug Chem. 2017 Apr 19;28(4):1214-1220. doi: 10.1021/acs.bioconjchem.7b00061. Epub 2017 Apr 5. Bioconjug Chem. 2017. PMID: 28332825

7

Folding Topology of a Short Coiled-Coil Peptide Structure Templated by an Oligonucleotide Triplex.

Lou C, Christensen NJ, Martos-Maldonado MC, Midtgaard SR, Ejlersen M, Thulstrup PW, Sørensen KK, Jensen KJ, Wengel J. Lou C, et al. Chemistry. 2017 Jul 12;23(39):9297-9305. doi: 10.1002/chem.201700971. Epub 2017 May 10. Chemistry. 2017. PMID: 28383784

8

Synergy of Two Highly Specific Biomolecular Recognition Events: Aligning an AT-Hook Peptide in DNA Minor Grooves via Covalent Conjugation to 2'-Amino-LNA.

Ejlersen M, Christensen NJ, Sørensen KK, Jensen KJ, Wengel J, Lou C. Ejlersen M, et al. Among authors: lou c. Bioconjug Chem. 2018 Apr 18;29(4):1025-1029. doi: 10.1021/acs.bioconjchem.8b00101. Epub 2018 Mar 13. Bioconjug Chem. 2018. PMID: 29505242

9

Modification of oligodeoxynucleotides by on-column Suzuki cross-coupling reactions.

Ejlersen M , Lou C , Sanghvi YS , Tor Y , Wengel J . Ejlersen M , et al. Among authors: lou c. Chem Commun (Camb). 2018 Jul 12;54(57):8003-8006. doi: 10.1039/c8cc01360h. Chem Commun (Camb). 2018. PMID: 29967912

10

Gapmer Antisense Oligonucleotides Containing 2',3'-Dideoxy-2'-fluoro-3'-C-hydroxymethyl-β-d-lyxofuranosyl Nucleotides Display Site-Specific RNase H Cleavage and Induce Gene Silencing.

Danielsen MB, Lou C, Lisowiec-Wachnicka J, Pasternak A, Jørgensen PT, Wengel J. Danielsen MB, et al. Among authors: lou c. Chemistry. 2020 Jan 27;26(6):1368-1379. doi: 10.1002/chem.201904540. Epub 2020 Jan 20. Chemistry. 2020. PMID: 31682037

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