Ernst M - Search Results

1

α6-Containing GABA_A Receptors: Functional Roles and Therapeutic Potentials.

Sieghart W, Chiou LC, Ernst M, Fabjan J, M Savić M, Lee MT. Sieghart W, et al. Among authors: m savic m, ernst m. Pharmacol Rev. 2022 Jan;74(1):238-270. doi: 10.1124/pharmrev.121.000293. Pharmacol Rev. 2022. PMID: 35017178 Review.

2

Comparative modeling of GABA(A) receptors: limits, insights, future developments.

Ernst M, Brauchart D, Boresch S, Sieghart W. Ernst M, et al. Neuroscience. 2003;119(4):933-43. doi: 10.1016/s0306-4522(03)00288-4. Neuroscience. 2003. PMID: 12831854 Review.

3

Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit.

Ogris W, Pöltl A, Hauer B, Ernst M, Oberto A, Wulff P, Höger H, Wisden W, Sieghart W. Ogris W, et al. Among authors: ernst m. Biochem Pharmacol. 2004 Oct 15;68(8):1621-9. doi: 10.1016/j.bcp.2004.07.020. Biochem Pharmacol. 2004. PMID: 15451405

4

Comparative models of GABAA receptor extracellular and transmembrane domains: important insights in pharmacology and function.

Ernst M, Bruckner S, Boresch S, Sieghart W. Ernst M, et al. Mol Pharmacol. 2005 Nov;68(5):1291-300. doi: 10.1124/mol.105.015982. Epub 2005 Aug 15. Mol Pharmacol. 2005. PMID: 16103045

5

Identification of amino acid residues important for assembly of GABA receptor alpha1 and gamma2 subunits.

Sarto-Jackson I, Ramerstorfer J, Ernst M, Sieghart W. Sarto-Jackson I, et al. Among authors: ernst m. J Neurochem. 2006 Feb;96(4):983-95. doi: 10.1111/j.1471-4159.2005.03626.x. Epub 2006 Jan 12. J Neurochem. 2006. PMID: 16412095 Free article.

6

Spontaneous cross-link of mutated alpha1 subunits during GABA(A) receptor assembly.

Sarto-Jackson I, Furtmueller R, Ernst M, Huck S, Sieghart W. Sarto-Jackson I, et al. Among authors: ernst m. J Biol Chem. 2007 Feb 16;282(7):4354-4363. doi: 10.1074/jbc.M609676200. Epub 2006 Dec 4. J Biol Chem. 2007. PMID: 17148454 Free article.

7

An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models.

Clayton T, Chen JL, Ernst M, Richter L, Cromer BA, Morton CJ, Ng H, Kaczorowski CC, Helmstetter FJ, Furtmüller R, Ecker G, Parker MW, Sieghart W, Cook JM. Clayton T, et al. Among authors: ernst m. Curr Med Chem. 2007;14(26):2755-75. doi: 10.2174/092986707782360097. Curr Med Chem. 2007. PMID: 18045122 Review.

8

The GABAA receptor alpha+beta- interface: a novel target for subtype selective drugs.

Ramerstorfer J, Furtmüller R, Sarto-Jackson I, Varagic Z, Sieghart W, Ernst M. Ramerstorfer J, et al. Among authors: ernst m. J Neurosci. 2011 Jan 19;31(3):870-7. doi: 10.1523/JNEUROSCI.5012-10.2011. J Neurosci. 2011. PMID: 21248110 Free PMC article.

9

A novel GABA(A) receptor pharmacology: drugs interacting with the α(+) β(-) interface.

Sieghart W, Ramerstorfer J, Sarto-Jackson I, Varagic Z, Ernst M. Sieghart W, et al. Among authors: ernst m. Br J Pharmacol. 2012 May;166(2):476-85. doi: 10.1111/j.1476-5381.2011.01779.x. Br J Pharmacol. 2012. PMID: 22074382 Free PMC article. Review.

10

Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands.

Richter L, de Graaf C, Sieghart W, Varagic Z, Mörzinger M, de Esch IJ, Ecker GF, Ernst M. Richter L, et al. Among authors: ernst m. Nat Chem Biol. 2012 Mar 25;8(5):455-64. doi: 10.1038/nchembio.917. Nat Chem Biol. 2012. PMID: 22446838 Free PMC article.

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