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RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1.
Abu-Libdeh B, Jhujh SS, Dhar S, Sommers JA, Datta A, Longo GM, Grange LJ, Reynolds JJ, Cooke SL, McNee GS, Hollingworth R, Woodward BL, Ganesh AN, Smerdon SJ, Nicolae CM, Durlacher-Betzer K, Molho-Pessach V, Abu-Libdeh A, Meiner V, Moldovan GL, Roukos V, Harel T, Brosh RM Jr, Stewart GS. Abu-Libdeh B, et al. Among authors: moldovan gl. J Clin Invest. 2022 Mar 1;132(5):e147301. doi: 10.1172/JCI147301. J Clin Invest. 2022. PMID: 35025765 Free PMC article.
Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination.
Wang YC, Kelso AA, Karamafrooz A, Chen YH, Chen WK, Cheng CT, Qi Y, Gu L, Malkas L, Kung HJ, Moldovan GL, Ciccia A, Stark JM, Ann DK. Wang YC, et al. Among authors: moldovan gl. bioRxiv [Preprint]. 2023 Feb 3:2023.01.31.526362. doi: 10.1101/2023.01.31.526362. bioRxiv. 2023. Update in: Cell Rep. 2023 Apr 25;42(4):112296. doi: 10.1016/j.celrep.2023.112296 PMID: 36778247 Free PMC article. Updated. Preprint.
Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination.
Wang YC, Kelso AA, Karamafrooz A, Chen YH, Chen WK, Cheng CT, Qi Y, Gu L, Malkas L, Taglialatela A, Kung HJ, Moldovan GL, Ciccia A, Stark JM, Ann DK. Wang YC, et al. Among authors: moldovan gl. Cell Rep. 2023 Apr 25;42(4):112296. doi: 10.1016/j.celrep.2023.112296. Epub 2023 Mar 23. Cell Rep. 2023. PMID: 36961817 Free PMC article.
PARI overexpression promotes genomic instability and pancreatic tumorigenesis.
O'Connor KW, Dejsuphong D, Park E, Nicolae CM, Kimmelman AC, D'Andrea AD, Moldovan GL. O'Connor KW, et al. Among authors: moldovan gl. Cancer Res. 2013 Apr 15;73(8):2529-39. doi: 10.1158/0008-5472.CAN-12-3313. Epub 2013 Feb 22. Cancer Res. 2013. PMID: 23436799 Free PMC article.
HUWE1 interacts with PCNA to alleviate replication stress.
Choe KN, Nicolae CM, Constantin D, Imamura Kawasawa Y, Delgado-Diaz MR, De S, Freire R, Smits VA, Moldovan GL. Choe KN, et al. Among authors: moldovan gl. EMBO Rep. 2016 Jun;17(6):874-86. doi: 10.15252/embr.201541685. Epub 2016 May 4. EMBO Rep. 2016. PMID: 27146073 Free PMC article.
PARP10 deficiency manifests by severe developmental delay and DNA repair defect.
Shahrour MA, Nicolae CM, Edvardson S, Ashhab M, Galvan AM, Constantin D, Abu-Libdeh B, Moldovan GL, Elpeleg O. Shahrour MA, et al. Among authors: moldovan gl. Neurogenetics. 2016 Oct;17(4):227-232. doi: 10.1007/s10048-016-0493-1. Epub 2016 Sep 13. Neurogenetics. 2016. PMID: 27624574 Free PMC article.
ERKing Trypanosoma: PCNA phosphorylation as novel target.
Nicolae CM, Moldovan GL. Nicolae CM, et al. Among authors: moldovan gl. Cell Cycle. 2016 Dec;15(23):3167-3168. doi: 10.1080/15384101.2016.1232081. Epub 2016 Sep 16. Cell Cycle. 2016. PMID: 27635479 Free PMC article. No abstract available.
65 results