Lappin KM - Search Results

1

Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors.

Lappin KM, Barros EM, Jhujh SS, Irwin GW, McMillan H, Liberante FG, Latimer C, La Bonte MJ, Mills KI, Harkin DP, Stewart GS, Savage KI. Lappin KM, et al. Cancer Res. 2022 Mar 1;82(5):819-830. doi: 10.1158/0008-5472.CAN-21-1843. Cancer Res. 2022. PMID: 35027467 Free PMC article.

2

Integrated analysis of the molecular action of Vorinostat identifies epi-sensitised targets for combination therapy.

Hay JF, Lappin K, Liberante F, Kettyle LM, Matchett KB, Thompson A, Mills KI. Hay JF, et al. Oncotarget. 2017 Jul 1;8(40):67891-67903. doi: 10.18632/oncotarget.18910. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978082 Free PMC article.

3

Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes.

Palau A, Garz AK, Diesch J, Zwick A, Malinverni R, Valero V, Lappin K, Casquero R, Lennartsson A, Zuber J, Navarro T, Mills KI, Götze KS, Buschbeck M. Palau A, et al. Oncotarget. 2017 Dec 1;8(70):115002-115017. doi: 10.18632/oncotarget.22839. eCollection 2017 Dec 29. Oncotarget. 2017. PMID: 29383137 Free PMC article.

4

Altered splicing and cytoplasmic levels of tRNA synthetases in SF3B1-mutant myelodysplastic syndromes as a therapeutic vulnerability.

Liberante FG, Lappin K, Barros EM, Vohhodina J, Grebien F, Savage KI, Mills KI. Liberante FG, et al. Sci Rep. 2019 Feb 25;9(1):2678. doi: 10.1038/s41598-019-39591-7. Sci Rep. 2019. PMID: 30804405 Free PMC article.

5

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML.

Smith JS, Lappin KM, Craig SG, Liberante FG, Crean CM, McDade SS, Thompson A, Mills KI, Savage KI. Smith JS, et al. Among authors: lappin km. J Transl Med. 2020 Sep 3;18(1):339. doi: 10.1186/s12967-020-02500-y. J Transl Med. 2020. PMID: 32883299 Free PMC article.

6

A compound combination screening approach with potential to identify new treatment options for paediatric acute myeloid leukaemia.

Lappin KM, Davis L, Matchett KB, Ge Y, Mills KI, Blayney JK. Lappin KM, et al. Sci Rep. 2020 Oct 28;10(1):18514. doi: 10.1038/s41598-020-75453-3. Sci Rep. 2020. PMID: 33116257 Free PMC article.

7

Erythropoietin in bone homeostasis-Implications for efficacious anemia therapy.

Lappin KM, Mills KI, Lappin TR. Lappin KM, et al. Stem Cells Transl Med. 2021 Jun;10(6):836-843. doi: 10.1002/sctm.20-0387. Epub 2021 Jan 21. Stem Cells Transl Med. 2021. PMID: 33475252 Free PMC article.

8

Multiplex Screening for Interacting Compounds in Paediatric Acute Myeloid Leukaemia.

Cairns LV, Lappin KM, Mutch A, Ali A, Matchett KB, Mills KI. Cairns LV, et al. Among authors: lappin km. Int J Mol Sci. 2021 Sep 21;22(18):10163. doi: 10.3390/ijms221810163. Int J Mol Sci. 2021. PMID: 34576326 Free PMC article.

9

Combination Therapies Targeting Apoptosis in Paediatric AML: Understanding the Molecular Mechanisms of AML Treatments Using Phosphoproteomics.

Ali AA, Cairns LV, Clarke KM, Blayney JK, Lappin KM, Mills KI. Ali AA, et al. Among authors: lappin km. Int J Mol Sci. 2023 Mar 16;24(6):5717. doi: 10.3390/ijms24065717. Int J Mol Sci. 2023. PMID: 36982791 Free PMC article.

10

Platelet Pathogen Reduction Technology-Should We Stay or Should We Go…?

Piccin A, Allameddine A, Spizzo G, Lappin KM, Prati D. Piccin A, et al. Among authors: lappin km. J Clin Med. 2024 Sep 10;13(18):5359. doi: 10.3390/jcm13185359. J Clin Med. 2024. PMID: 39336845 Free PMC article.

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