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JIB-04 Has Broad-Spectrum Antiviral Activity and Inhibits SARS-CoV-2 Replication and Coronavirus Pathogenesis.
Son J, Huang S, Zeng Q, Bricker TL, Case JB, Zhou J, Zang R, Liu Z, Chang X, Darling TL, Xu J, Harastani HH, Chen L, Gomez Castro MF, Zhao Y, Kohio HP, Hou G, Fan B, Niu B, Guo R, Rothlauf PW, Bailey AL, Wang X, Shi PY, Martinez ED, Brody SL, Whelan SPJ, Diamond MS, Boon ACM, Li B, Ding S. Son J, et al. Among authors: brody sl. mBio. 2022 Feb 22;13(1):e0337721. doi: 10.1128/mbio.03377-21. Epub 2022 Jan 18. mBio. 2022. PMID: 35038906 Free PMC article.
The translational landscape of SARS-CoV-2 and infected cells.
Puray-Chavez M, Lee N, Tenneti K, Wang Y, Vuong HR, Liu Y, Horani A, Huang T, Gunsten SP, Case JB, Yang W, Diamond MS, Brody SL, Dougherty J, Kutluay SB. Puray-Chavez M, et al. Among authors: brody sl. bioRxiv [Preprint]. 2021 Oct 7:2020.11.03.367516. doi: 10.1101/2020.11.03.367516. bioRxiv. 2021. Update in: mBio. 2022 Jun 28;13(3):e0081522. doi: 10.1128/mbio.00815-22 PMID: 33173862 Free PMC article. Updated. Preprint.
Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell.
Puray-Chavez M, LaPak KM, Schrank TP, Elliott JL, Bhatt DP, Agajanian MJ, Jasuja R, Lawson DQ, Davis K, Rothlauf PW, Jo H, Lee N, Tenneti K, Eschbach JE, Mugisha CS, Vuong HR, Bailey AL, Hayes DN, Whelan SPJ, Horani A, Brody SL, Goldfarb D, Major MB, Kutluay SB. Puray-Chavez M, et al. Among authors: brody sl. bioRxiv [Preprint]. 2021 Mar 1:2021.03.01.433431. doi: 10.1101/2021.03.01.433431. bioRxiv. 2021. Update in: Cell Rep. 2021 Jul 13;36(2):109364. doi: 10.1016/j.celrep.2021.109364 PMID: 33688646 Free PMC article. Updated. Preprint.
Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell.
Puray-Chavez M, LaPak KM, Schrank TP, Elliott JL, Bhatt DP, Agajanian MJ, Jasuja R, Lawson DQ, Davis K, Rothlauf PW, Liu Z, Jo H, Lee N, Tenneti K, Eschbach JE, Shema Mugisha C, Cousins EM, Cloer EW, Vuong HR, VanBlargan LA, Bailey AL, Gilchuk P, Crowe JE Jr, Diamond MS, Hayes DN, Whelan SPJ, Horani A, Brody SL, Goldfarb D, Major MB, Kutluay SB. Puray-Chavez M, et al. Among authors: brody sl. Cell Rep. 2021 Jul 13;36(2):109364. doi: 10.1016/j.celrep.2021.109364. Epub 2021 Jun 23. Cell Rep. 2021. PMID: 34214467 Free PMC article.
A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models.
Puray-Chavez M, Eschbach JE, Xia M, LaPak KM, Zhou Q, Jasuja R, Pan J, Xu J, Zhou Z, Mohammed S, Wang Q, Lawson DQ, Djokic S, Hou G, Ding S, Brody SL, Major MB, Goldfarb D, Kutluay SB. Puray-Chavez M, et al. Among authors: brody sl. Nat Commun. 2024 Sep 27;15(1):8394. doi: 10.1038/s41467-024-52803-7. Nat Commun. 2024. PMID: 39333139 Free PMC article.
Myb permits multilineage airway epithelial cell differentiation.
Pan JH, Adair-Kirk TL, Patel AC, Huang T, Yozamp NS, Xu J, Reddy EP, Byers DE, Pierce RA, Holtzman MJ, Brody SL. Pan JH, et al. Among authors: brody sl. Stem Cells. 2014 Dec;32(12):3245-56. doi: 10.1002/stem.1814. Stem Cells. 2014. PMID: 25103188 Free PMC article.
Engineering rotating apical-out airway organoid for assessing respiratory cilia motility.
Wijesekara P, Yadav P, Perkins LA, Stolz DB, Franks JM, Watkins SC, Reinoso Jacome E, Brody SL, Horani A, Xu J, Barati Farimani A, Ren X. Wijesekara P, et al. Among authors: brody sl. iScience. 2022 Jul 9;25(8):104730. doi: 10.1016/j.isci.2022.104730. eCollection 2022 Aug 19. iScience. 2022. PMID: 35942088 Free PMC article.
A basally active cGAS-STING pathway limits SARS-CoV-2 replication in a subset of ACE2 positive airway cell models.
Puray-Chavez M, Eschbach JE, Xia M, LaPak KM, Zhou Q, Jasuja R, Pan J, Xu J, Zhou Z, Mohammed S, Wang Q, Lawson DQ, Djokic S, Hou G, Ding S, Brody SL, Major MB, Goldfarb D, Kutluay SB. Puray-Chavez M, et al. Among authors: brody sl. bioRxiv [Preprint]. 2024 Sep 6:2024.01.07.574522. doi: 10.1101/2024.01.07.574522. bioRxiv. 2024. Update in: Nat Commun. 2024 Sep 27;15(1):8394. doi: 10.1038/s41467-024-52803-7 PMID: 38260460 Free PMC article. Updated. Preprint.
174 results