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A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium.
Ferrer M, Corneo B, Davis J, Wan Q, Miyagishima KJ, King R, Maminishkis A, Marugan J, Sharma R, Shure M, Temple S, Miller S, Bharti K. Ferrer M, et al. Among authors: bharti k. Stem Cells Transl Med. 2014 Aug;3(8):911-22. doi: 10.5966/sctm.2013-0192. Epub 2014 May 29. Stem Cells Transl Med. 2014. PMID: 24873859 Free PMC article.
Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model.
Sharma R, George A, Nimmagadda M, Ortolan D, Karla BS, Qureshy Z, Bose D, Dejene R, Liang G, Wan Q, Chang J, Jha BS, Memon O, Miyagishima KJ, Rising A, Lal M, Hanson E, King R, Campos MM, Ferrer M, Amaral J, McGaughey D, Bharti K. Sharma R, et al. Among authors: bharti k. Nat Commun. 2021 Dec 15;12(1):7293. doi: 10.1038/s41467-021-27488-x. Nat Commun. 2021. PMID: 34911940 Free PMC article.
Bioprinted 3D outer retina barrier uncovers RPE-dependent choroidal phenotype in advanced macular degeneration.
Song MJ, Quinn R, Nguyen E, Hampton C, Sharma R, Park TS, Koster C, Voss T, Tristan C, Weber C, Singh A, Dejene R, Bose D, Chen YC, Derr P, Derr K, Michael S, Barone F, Chen G, Boehm M, Maminishkis A, Singec I, Ferrer M, Bharti K. Song MJ, et al. Among authors: bharti k. Nat Methods. 2023 Jan;20(1):149-161. doi: 10.1038/s41592-022-01701-1. Epub 2022 Dec 22. Nat Methods. 2023. PMID: 36550275
Patching the retina with stem cells.
Bharti K. Bharti K. Nat Biotechnol. 2018 Apr 5;36(4):311-313. doi: 10.1038/nbt.4118. Nat Biotechnol. 2018. PMID: 29621220 Free PMC article.
Generation of an inducible RPE-specific Cre transgenic-mouse line.
Schneider S, Hotaling N, Campos M, Patnaik SR, Bharti K, May-Simera HL. Schneider S, et al. Among authors: bharti k. PLoS One. 2018 Nov 15;13(11):e0207222. doi: 10.1371/journal.pone.0207222. eCollection 2018. PLoS One. 2018. PMID: 30440011 Free PMC article.
Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells.
Maruotti J, Sripathi SR, Bharti K, Fuller J, Wahlin KJ, Ranganathan V, Sluch VM, Berlinicke CA, Davis J, Kim C, Zhao L, Wan J, Qian J, Corneo B, Temple S, Dubey R, Olenyuk BZ, Bhutto I, Lutty GA, Zack DJ. Maruotti J, et al. Among authors: bharti k. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):10950-5. doi: 10.1073/pnas.1422818112. Epub 2015 Aug 12. Proc Natl Acad Sci U S A. 2015. PMID: 26269569 Free PMC article.
160 results