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Neurological Response to cART vs. cART plus Integrase Inhibitor and CCR5 Antagonist Initiated during Acute HIV.
Valcour VG, Spudich SS, Sailasuta N, Phanuphak N, Lerdlum S, Fletcher JL, Kroon ED, Jagodzinski LL, Allen IE, Adams CL, Prueksakaew P, Slike BM, Hellmuth JM, Kim JH, Ananworanich J; SEARCH 010/RV 254 Study Group. Valcour VG, et al. Among authors: hellmuth jm. PLoS One. 2015 Nov 10;10(11):e0142600. doi: 10.1371/journal.pone.0142600. eCollection 2015. PLoS One. 2015. PMID: 26555069 Free PMC article. Clinical Trial.
Neurologic signs and symptoms frequently manifest in acute HIV infection.
Hellmuth J, Fletcher JL, Valcour V, Kroon E, Ananworanich J, Intasan J, Lerdlum S, Narvid J, Pothisri M, Allen I, Krebs SJ, Slike B, Prueksakaew P, Jagodzinski LL, Puttamaswin S, Phanuphak N, Spudich S; SEARCH 010/RV254 Study Group. Hellmuth J, et al. Neurology. 2016 Jul 12;87(2):148-54. doi: 10.1212/WNL.0000000000002837. Epub 2016 Jun 10. Neurology. 2016. PMID: 27287217 Free PMC article.
Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection.
Peluso MJ, Valcour V, Phanuphak N, Ananworanich J, Fletcher JL, Chalermchai T, Krebs SJ, Robb ML, Hellmuth J, Gisslén M, Zetterberg H, Spudich S; RV254SEARCH 010, RV304SEARCH 013, and SEARCH 011 Study Teams. Peluso MJ, et al. Among authors: hellmuth j. AIDS. 2017 Jan 14;31(2):247-252. doi: 10.1097/QAD.0000000000001314. AIDS. 2017. PMID: 27819802 Free PMC article.
114 results