Lu L - Search Results

1

Tumor Microenvironment Acidity Triggers Lipid Accumulation in Liver Cancer via SCD1 Activation.

Ding M, Zhang S, Guo Y, Yao J, Shen Q, Huang M, Chen W, Yu S, Zheng Y, Lin Y, Yan W, Liu Z, Su T, Lu L. Ding M, et al. Among authors: lu l. Mol Cancer Res. 2022 May 4;20(5):810-822. doi: 10.1158/1541-7786.MCR-21-0699. Mol Cancer Res. 2022. PMID: 35046108

2

Monoester-Diterpene Aconitum Alkaloid Metabolism in Human Liver Microsomes: Predominant Role of CYP3A4 and CYP3A5.

Ye L, Yang XS, Lu LL, Chen WY, Zeng S, Yan TM, Dong LN, Peng XJ, Shi J, Liu ZQ. Ye L, et al. Among authors: lu ll. Evid Based Complement Alternat Med. 2013;2013:941093. doi: 10.1155/2013/941093. Epub 2013 Jun 23. Evid Based Complement Alternat Med. 2013. PMID: 23864901 Free PMC article.

3

Sorafenib metabolism is significantly altered in the liver tumor tissue of hepatocellular carcinoma patient.

Ye L, Yang X, Guo E, Chen W, Lu L, Wang Y, Peng X, Yan T, Zhou F, Liu Z. Ye L, et al. Among authors: lu l. PLoS One. 2014 May 5;9(5):e96664. doi: 10.1371/journal.pone.0096664. eCollection 2014. PLoS One. 2014. PMID: 24797816 Free PMC article.

4

Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method.

Yan T, Gao S, Peng X, Shi J, Xie C, Li Q, Lu L, Wang Y, Zhou F, Liu Z, Hu M. Yan T, et al. Among authors: lu l. Pharm Res. 2015 Mar;32(3):1141-57. doi: 10.1007/s11095-014-1525-x. Epub 2014 Oct 8. Pharm Res. 2015. PMID: 25288013 Free PMC article.

5

Coadministration of Pinellia ternata Can Significantly Reduce Aconitum carmichaelii to Inhibit CYP3A Activity in Rats.

Wu J, Cheng Z, Zhu L, Lu L, Zhang G, Wang Y, Xu Y, Lin N, Liu Z. Wu J, et al. Among authors: lu l. Evid Based Complement Alternat Med. 2014;2014:734867. doi: 10.1155/2014/734867. Epub 2014 Oct 14. Evid Based Complement Alternat Med. 2014. PMID: 25371696 Free PMC article.

6

The influences of aconitine, an active/toxic alkaloid from aconitum, on the oral pharmacokinetics of CYP3A probe drug buspirone in rats.

Zhu L, Lu L, Guo E, Wu J, Wang Y, Hu M, Liu Z. Zhu L, et al. Among authors: lu l. Drug Metab Lett. 2014;8(2):135-44. doi: 10.2174/1872312808666140505162139. Drug Metab Lett. 2014. PMID: 25434398

7

Pinelliae rhizoma, a toxic chinese herb, can significantly inhibit CYP3A activity in rats.

Wu J, Cheng Z, He S, Shi J, Liu S, Zhang G, Zhu L, Liu L, Liu Z, Lin N, Lu L. Wu J, et al. Among authors: lu l. Molecules. 2015 Jan 7;20(1):792-806. doi: 10.3390/molecules20010792. Molecules. 2015. PMID: 25574821 Free PMC article.

8

Multidrug resistance-associated protein 2 is involved in the efflux of Aconitum alkaloids determined by MRP2-MDCKII cells.

Dai P, Zhu L, Yang X, Zhao M, Shi J, Wang Y, Lu L, Liu Z. Dai P, et al. Among authors: lu l. Life Sci. 2015 Apr 15;127:66-72. doi: 10.1016/j.lfs.2015.02.011. Epub 2015 Mar 2. Life Sci. 2015. PMID: 25744397

9

Triple Recycling Processes Impact Systemic and Local Bioavailability of Orally Administered Flavonoids.

Dai P, Zhu L, Luo F, Lu L, Li Q, Wang L, Wang Y, Wang X, Hu M, Liu Z. Dai P, et al. Among authors: lu l. AAPS J. 2015 May;17(3):723-36. doi: 10.1208/s12248-015-9732-x. Epub 2015 Mar 12. AAPS J. 2015. PMID: 25762448 Free PMC article.

10

UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes.

Zhu L, Lu L, Zeng S, Luo F, Dai P, Wu P, Wang Y, Liu L, Hu M, Liu Z. Zhu L, et al. Among authors: lu l. Drug Metab Dispos. 2015 Jul;43(7):977-83. doi: 10.1124/dmd.115.063552. Epub 2015 Apr 8. Drug Metab Dispos. 2015. PMID: 25854527 Free PMC article.

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