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Page 1
MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells.
Limagne E, Nuttin L, Thibaudin M, Jacquin E, Aucagne R, Bon M, Revy S, Barnestein R, Ballot E, Truntzer C, Derangère V, Fumet JD, Latour C, Rébé C, Bellaye PS, Kaderbhaï CG, Spill A, Collin B, Callanan MB, Lagrange A, Favier L, Coudert B, Arnould L, Ladoire S, Routy B, Joubert P, Ghiringhelli F. Limagne E, et al. Among authors: nuttin l. Cancer Cell. 2022 Feb 14;40(2):136-152.e12. doi: 10.1016/j.ccell.2021.12.009. Epub 2022 Jan 19. Cancer Cell. 2022. PMID: 35051357 Free article.
Development of a successful antitumor therapeutic model combining in vivo dendritic cell vaccination with tumor irradiation and intratumoral GM-CSF delivery.
Driessens G, Nuttin L, Gras A, Maetens J, Mievis S, Schoore M, Velu T, Tenenbaum L, Préat V, Bruyns C. Driessens G, et al. Among authors: nuttin l. Cancer Immunol Immunother. 2011 Feb;60(2):273-81. doi: 10.1007/s00262-010-0941-y. Epub 2010 Nov 13. Cancer Immunol Immunother. 2011. PMID: 21076828 Free PMC article.
Therapeutic efficacy of antitumor dendritic cell vaccinations correlates with persistent Th1 responses, high intratumor CD8+ T cell recruitment and low relative regulatory T cell infiltration.
Driessens G, Gordower L, Nuttin L, Stordeur P, Blocklet D, Egrise D, Velu T, Bruyns C. Driessens G, et al. Among authors: nuttin l. Cancer Immunol Immunother. 2008 Dec;57(12):1745-56. doi: 10.1007/s00262-008-0500-y. Epub 2008 Mar 28. Cancer Immunol Immunother. 2008. PMID: 18369621 Free PMC article.