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NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.
Biebl MM, Delhommel F, Faust O, Zak KM, Agam G, Guo X, Mühlhofer M, Dahiya V, Hillebrand D, Popowicz GM, Kampmann M, Lamb DC, Rosenzweig R, Sattler M, Buchner J. Biebl MM, et al. Among authors: kampmann m. Mol Cell. 2022 Feb 3;82(3):555-569.e7. doi: 10.1016/j.molcel.2021.12.031. Epub 2022 Jan 20. Mol Cell. 2022. PMID: 35063133 Free article.
Selective vulnerabilities in the proteostasis network of castration-resistant prostate cancer.
Shkedi A, Taylor IR, Echtenkamp F, Ramkumar P, Alshalalfa M, Rivera-Márquez GM, Moses MA, Shao H, Karnes RJ, Neckers L, Feng F, Kampmann M, Gestwicki JE. Shkedi A, et al. Among authors: kampmann m. Cell Chem Biol. 2022 Mar 17;29(3):490-501.e4. doi: 10.1016/j.chembiol.2022.01.008. Epub 2022 Feb 1. Cell Chem Biol. 2022. PMID: 35108506 Free PMC article.
Pharmacologic Activation of a Compensatory Integrated Stress Response Kinase Promotes Mitochondrial Remodeling in PERK-deficient Cells.
Perea V, Baron KR, Dolina V, Aviles G, Rosarda JD, Guo X, Kampmann M, Wiseman RL. Perea V, et al. Among authors: kampmann m. bioRxiv [Preprint]. 2023 May 17:2023.03.11.532186. doi: 10.1101/2023.03.11.532186. bioRxiv. 2023. Update in: Cell Chem Biol. 2023 Dec 21;30(12):1571-1584.e5. doi: 10.1016/j.chembiol.2023.10.006 PMID: 36945406 Free PMC article. Updated. Preprint.
DELE1 oligomerization promotes integrated stress response activation.
Yang J, Baron KR, Pride DE, Schneemann A, Guo X, Chen W, Song AS, Aviles G, Kampmann M, Wiseman RL, Lander GC. Yang J, et al. Among authors: kampmann m. Nat Struct Mol Biol. 2023 Sep;30(9):1295-1302. doi: 10.1038/s41594-023-01061-0. Epub 2023 Aug 7. Nat Struct Mol Biol. 2023. PMID: 37550454 Free PMC article.
178 results