Kuo CC - Search Results

1

Selective stabilization of the intermediate inactivated Na⁺ channel by the new-generation anticonvulsant rufinamide.

Lin YC, Lai YC, Lin TH, Yang YC, Kuo CC. Lin YC, et al. Among authors: kuo cc. Biochem Pharmacol. 2022 Mar;197:114928. doi: 10.1016/j.bcp.2022.114928. Epub 2022 Jan 19. Biochem Pharmacol. 2022. PMID: 35063442

2

Carbamazepine inhibition of neuronal Na+ currents: quantitative distinction from phenytoin and possible therapeutic implications.

Kuo CC, Chen RS, Lu L, Chen RC. Kuo CC, et al. Mol Pharmacol. 1997 Jun;51(6):1077-83. doi: 10.1124/mol.51.6.1077. Mol Pharmacol. 1997. PMID: 9187275

3

Characterization of lamotrigine inhibition of Na+ channels in rat hippocampal neurones.

Kuo CC, Lu L. Kuo CC, et al. Br J Pharmacol. 1997 Jul;121(6):1231-8. doi: 10.1038/sj.bjp.0701221. Br J Pharmacol. 1997. PMID: 9249262 Free PMC article.

4

A common anticonvulsant binding site for phenytoin, carbamazepine, and lamotrigine in neuronal Na+ channels.

Kuo CC. Kuo CC. Mol Pharmacol. 1998 Oct;54(4):712-21. Mol Pharmacol. 1998. PMID: 9765515

5

Inhibition of Na(+) current by diphenhydramine and other diphenyl compounds: molecular determinants of selective binding to the inactivated channels.

Kuo CC, Huang RC, Lou BS. Kuo CC, et al. Mol Pharmacol. 2000 Jan;57(1):135-43. Mol Pharmacol. 2000. PMID: 10617688

6

Inhibition of Na(+) current by imipramine and related compounds: different binding kinetics as an inactivation stabilizer and as an open channel blocker.

Yang YC, Kuo CC. Yang YC, et al. Among authors: kuo cc. Mol Pharmacol. 2002 Nov;62(5):1228-37. doi: 10.1124/mol.62.5.1228. Mol Pharmacol. 2002. PMID: 12391287

7

The position of the fourth segment of domain 4 determines status of the inactivation gate in Na+ channels.

Yang YC, Kuo CC. Yang YC, et al. Among authors: kuo cc. J Neurosci. 2003 Jun 15;23(12):4922-30. doi: 10.1523/JNEUROSCI.23-12-04922.2003. J Neurosci. 2003. PMID: 12832514 Free PMC article.

8

Use-dependent inhibition of the N-methyl-D-aspartate currents by felbamate: a gating modifier with selective binding to the desensitized channels.

Kuo CC, Lin BJ, Chang HR, Hsieh CP. Kuo CC, et al. Mol Pharmacol. 2004 Feb;65(2):370-80. doi: 10.1124/mol.65.2.370. Mol Pharmacol. 2004. PMID: 14742679

9

Block of tetrodotoxin-resistant Na+ channel pore by multivalent cations: gating modification and Na+ flow dependence.

Kuo CC, Chen WY, Yang YC. Kuo CC, et al. J Gen Physiol. 2004 Jul;124(1):27-42. doi: 10.1085/jgp.200409054. J Gen Physiol. 2004. PMID: 15226363 Free PMC article.

10

An inactivation stabilizer of the Na+ channel acts as an opportunistic pore blocker modulated by external Na+.

Yang YC, Kuo CC. Yang YC, et al. Among authors: kuo cc. J Gen Physiol. 2005 May;125(5):465-81. doi: 10.1085/jgp.200409156. Epub 2005 Apr 11. J Gen Physiol. 2005. PMID: 15824190 Free PMC article.

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