Chen XJ - Search Results

1

Cytosolic adaptation to mitochondria-induced proteostatic stress causes progressive muscle wasting.

Wang X, Middleton FA, Tawil R, Chen XJ. Wang X, et al. Among authors: chen xj. iScience. 2021 Dec 31;25(1):103715. doi: 10.1016/j.isci.2021.103715. eCollection 2022 Jan 21. iScience. 2021. PMID: 35072007 Free PMC article.

2

A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death.

Wang X, Chen XJ. Wang X, et al. Among authors: chen xj. Nature. 2015 Aug 27;524(7566):481-4. doi: 10.1038/nature14859. Epub 2015 Jul 20. Nature. 2015. PMID: 26192197 Free PMC article.

3

Misfolding of mutant adenine nucleotide translocase in yeast supports a novel mechanism of Ant1-induced muscle diseases.

Liu Y, Wang X, Chen XJ. Liu Y, et al. Among authors: chen xj. Mol Biol Cell. 2015 Jun 1;26(11):1985-94. doi: 10.1091/mbc.E15-01-0030. Epub 2015 Apr 1. Mol Biol Cell. 2015. PMID: 25833713 Free PMC article.

4

Mitochondrial carrier protein overloading and misfolding induce aggresomes and proteostatic adaptations in the cytosol.

Liu Y, Wang X, Coyne LP, Yang Y, Qi Y, Middleton FA, Chen XJ. Liu Y, et al. Among authors: chen xj. Mol Biol Cell. 2019 May 15;30(11):1272-1284. doi: 10.1091/mbc.E19-01-0046. Epub 2019 Mar 20. Mol Biol Cell. 2019. PMID: 30893019 Free PMC article.

5

Reduced cytosolic protein synthesis suppresses mitochondrial degeneration.

Wang X, Zuo X, Kucejova B, Chen XJ. Wang X, et al. Among authors: chen xj. Nat Cell Biol. 2008 Sep;10(9):1090-7. doi: 10.1038/ncb1769. Nat Cell Biol. 2008. PMID: 19160490 Free PMC article.

6

Dominant membrane uncoupling by mutant adenine nucleotide translocase in mitochondrial diseases.

Wang X, Salinas K, Zuo X, Kucejova B, Chen XJ. Wang X, et al. Among authors: chen xj. Hum Mol Genet. 2008 Dec 15;17(24):4036-44. doi: 10.1093/hmg/ddn306. Epub 2008 Sep 22. Hum Mol Genet. 2008. PMID: 18809618 Free PMC article.

7

A properly configured ring structure is critical for the function of the mitochondrial DNA recombination protein, Mgm101.

Nardozzi JD, Wang X, Mbantenkhu M, Wilkens S, Chen XJ. Nardozzi JD, et al. Among authors: chen xj. J Biol Chem. 2012 Oct 26;287(44):37259-68. doi: 10.1074/jbc.M112.389965. Epub 2012 Sep 4. J Biol Chem. 2012. PMID: 22948312 Free PMC article.

8

Preparation of the Mgm101 recombination protein by MBP-based tagging strategy.

Wang X, Mbantenkhu M, Wierzbicki S, Chen XJ. Wang X, et al. Among authors: chen xj. J Vis Exp. 2013 Jun 25;(76):50448. doi: 10.3791/50448. J Vis Exp. 2013. PMID: 23851592 Free PMC article.

9

Yeast aconitase binds and provides metabolically coupled protection to mitochondrial DNA.

Chen XJ, Wang X, Butow RA. Chen XJ, et al. Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13738-43. doi: 10.1073/pnas.0703078104. Epub 2007 Aug 14. Proc Natl Acad Sci U S A. 2007. PMID: 17698960 Free PMC article.

10

A short carboxyl-terminal tail is required for single-stranded DNA binding, higher-order structural organization, and stability of the mitochondrial single-stranded annealing protein Mgm101.

Mbantenkhu M, Wierzbicki S, Wang X, Guo S, Wilkens S, Chen XJ. Mbantenkhu M, et al. Among authors: chen xj. Mol Biol Cell. 2013 May;24(10):1507-18. doi: 10.1091/mbc.E13-01-0006. Epub 2013 Mar 27. Mol Biol Cell. 2013. PMID: 23536705 Free PMC article.

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