Yang G - Search Results

1

One-Pot Enzymatic Synthesis and Biological Evaluation of Ganglioside GM3 Derivatives as Potential Cancer Immunotherapeutics.

Wang J, Lu D, Sun R, Lei S, Luo S, Dang X, Zhang Y, Yuan C, Zhang Y, Wu J, Yang G, Fu L, Jiang F. Wang J, et al. Among authors: yang g. J Med Chem. 2022 Feb 10;65(3):1883-1897. doi: 10.1021/acs.jmedchem.1c01301. Epub 2022 Jan 24. J Med Chem. 2022. PMID: 35073068

2

Enhanced enzyme kinetic stability by increasing rigidity within the active site.

Xie Y, An J, Yang G, Wu G, Zhang Y, Cui L, Feng Y. Xie Y, et al. Among authors: yang g. J Biol Chem. 2014 Mar 14;289(11):7994-8006. doi: 10.1074/jbc.M113.536045. Epub 2014 Jan 21. J Biol Chem. 2014. PMID: 24448805 Free PMC article.

3

Structure features of GH10 xylanase from Caldicellulosiruptor bescii: implication for its thermophilic adaption and substrate binding preference.

Zhang Y, An J, Yang G, Zhang X, Xie Y, Chen L, Feng Y. Zhang Y, et al. Among authors: yang g. Acta Biochim Biophys Sin (Shanghai). 2016 Oct;48(10):948-957. doi: 10.1093/abbs/gmw086. Epub 2016 Aug 25. Acta Biochim Biophys Sin (Shanghai). 2016. PMID: 27563004 Free article.

4

A general and efficient strategy for generating the stable enzymes.

Zhang XF, Yang GY, Zhang Y, Xie Y, Withers SG, Feng Y. Zhang XF, et al. Among authors: yang gy. Sci Rep. 2016 Sep 26;6:33797. doi: 10.1038/srep33797. Sci Rep. 2016. PMID: 27667190 Free PMC article.

5

Stepwise Loop Insertion Strategy for Active Site Remodeling to Generate Novel Enzyme Functions.

Hoque MA, Zhang Y, Chen L, Yang G, Khatun MA, Chen H, Hao L, Feng Y. Hoque MA, et al. Among authors: yang g. ACS Chem Biol. 2017 May 19;12(5):1188-1193. doi: 10.1021/acschembio.7b00018. Epub 2017 Mar 27. ACS Chem Biol. 2017. PMID: 28323400

6

Structure of an endogalactosylceramidase from Rhodococcus hoagii 103S reveals the molecular basis of its substrate specificity.

Chen L, Chang Q, Yan Q, Yang G, Zhang Y, Feng Y. Chen L, et al. Among authors: yang g. J Struct Biol. 2019 Dec 1;208(3):107393. doi: 10.1016/j.jsb.2019.09.010. Epub 2019 Sep 23. J Struct Biol. 2019. PMID: 31557527

7

Design, synthesis and neurite outgrowth activity of novel ganglioside GM1 derivatives by remodeling of the fatty acid moiety.

Chen X, Jin X, Huang F, Wang J, Cao X, Wang PG, Feng Y, Jiang F, Yang G. Chen X, et al. Among authors: yang g. Eur J Med Chem. 2022 Nov 5;241:114636. doi: 10.1016/j.ejmech.2022.114636. Epub 2022 Aug 1. Eur J Med Chem. 2022. PMID: 35952400 Free article.

8

Modulation of the thermostability and substrate specificity of Candida rugosa lipase1 by altering the acyl-binding residue Gly414 at the α-helix-connecting bend.

Zhang X, Zhang Y, Yang G, Xie Y, Xu L, An J, Cui L, Feng Y. Zhang X, et al. Among authors: yang g. Enzyme Microb Technol. 2016 Jan;82:34-41. doi: 10.1016/j.enzmictec.2015.08.006. Epub 2015 Aug 14. Enzyme Microb Technol. 2016. PMID: 26672446

9

Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases.

Han YB, Chen LQ, Li Z, Tan YM, Feng Y, Yang GY. Han YB, et al. J Biol Chem. 2017 Mar 24;292(12):4789-4800. doi: 10.1074/jbc.M116.763821. Epub 2017 Feb 8. J Biol Chem. 2017. PMID: 28179425 Free PMC article.

10

Directed evolution of an α1,3-fucosyltransferase using a single-cell ultrahigh-throughput screening method.

Tan Y, Zhang Y, Han Y, Liu H, Chen H, Ma F, Withers SG, Feng Y, Yang G. Tan Y, et al. Among authors: yang g. Sci Adv. 2019 Oct 9;5(10):eaaw8451. doi: 10.1126/sciadv.aaw8451. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31633018 Free PMC article.

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