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Tumor suppressor CEBPA interacts with and inhibits DNMT3A activity.
Chen X, Zhou W, Song RH, Liu S, Wang S, Chen Y, Gao C, He C, Xiao J, Zhang L, Wang T, Liu P, Duan K, Cheng Z, Zhang C, Zhang J, Sun Y, Jackson F, Lan F, Liu Y, Xu Y, Wong JJ, Wang P, Yang H, Xiong Y, Chen T, Li Y, Ye D. Chen X, et al. Among authors: cheng z. Sci Adv. 2022 Jan 28;8(4):eabl5220. doi: 10.1126/sciadv.abl5220. Epub 2022 Jan 26. Sci Adv. 2022. PMID: 35080973 Free PMC article.
SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.
Chen LL, Lin HP, Zhou WJ, He CX, Zhang ZY, Cheng ZL, Song JB, Liu P, Chen XY, Xia YK, Chen XF, Sun RQ, Zhang JY, Sun YP, Song L, Liu BJ, Du RK, Ding C, Lan F, Huang SL, Zhou F, Liu S, Xiong Y, Ye D, Guan KL. Chen LL, et al. Cell Rep. 2018 Nov 6;25(6):1485-1500.e4. doi: 10.1016/j.celrep.2018.10.028. Cell Rep. 2018. PMID: 30404004 Free PMC article.
The Zscan4-Tet2 Transcription Nexus Regulates Metabolic Rewiring and Enhances Proteostasis to Promote Reprogramming.
Cheng ZL, Zhang ML, Lin HP, Gao C, Song JB, Zheng Z, Li L, Zhang Y, Shen X, Zhang H, Huang Z, Zhan W, Zhang C, Hu X, Sun YP, Jiang L, Sun L, Xu Y, Yang C, Ge Y, Zhao Y, Liu X, Yang H, Liu P, Guo X, Guan KL, Xiong Y, Zhang M, Ye D. Cheng ZL, et al. Cell Rep. 2020 Jul 14;32(2):107877. doi: 10.1016/j.celrep.2020.107877. Cell Rep. 2020. PMID: 32668244 Free article.
Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses.
Chen LL, Morcelle C, Cheng ZL, Chen X, Xu Y, Gao Y, Song J, Li Z, Smith MD, Shi M, Zhu Y, Zhou N, Cheng M, He C, Liu KY, Lu G, Zhang L, Zhang C, Zhang J, Sun Y, Qi T, Lyu Y, Ren ZZ, Tan XM, Yin J, Lan F, Liu Y, Yang H, Qian M, Duan C, Chang X, Zhou Y, Shen L, Baldwin AS, Guan KL, Xiong Y, Ye D. Chen LL, et al. Among authors: cheng m, cheng zl. Nat Cell Biol. 2022 Mar;24(3):353-363. doi: 10.1038/s41556-022-00853-8. Epub 2022 Mar 7. Nat Cell Biol. 2022. PMID: 35256775 Free PMC article.
Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy.
Chen YJ, Li GN, Li XJ, Wei LX, Fu MJ, Cheng ZL, Yang Z, Zhu GQ, Wang XD, Zhang C, Zhang JY, Sun YP, Saiyin H, Zhang J, Liu WR, Zhu WW, Guan KL, Xiong Y, Yang Y, Ye D, Chen LL. Chen YJ, et al. Among authors: cheng zl. Sci Adv. 2023 Apr 28;9(17):eadg0654. doi: 10.1126/sciadv.adg0654. Epub 2023 Apr 28. Sci Adv. 2023. PMID: 37115931 Free PMC article.
Impact of acetylation on tumor metabolism.
Zhao D, Li FL, Cheng ZL, Lei QY. Zhao D, et al. Mol Cell Oncol. 2014 Oct 29;1(3):e963452. doi: 10.4161/23723548.2014.963452. eCollection 2014 Jul-Sep. Mol Cell Oncol. 2014. PMID: 27308346 Free PMC article. Review.
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