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A prospective observational study of on-treatment plasma homocysteine levels as a biomarker of toxicity, depression and vitamin supplementation lead-in time pre pemetrexed, in patients with non-small cell lung cancer and malignant mesothelioma.
Minchom A, Mak D, Gunapala R, Walder D, Kumar R, Yousaf N, Hodgkiss A, Bhosle J, Popat S, O'Brien MER. Minchom A, et al. Among authors: gunapala r. PLoS One. 2019 Nov 25;14(11):e0225509. doi: 10.1371/journal.pone.0225509. eCollection 2019. PLoS One. 2019. PMID: 31765437 Free PMC article.
A randomised study comparing the effectiveness of acupuncture or morphine versus the combination for the relief of dyspnoea in patients with advanced non-small cell lung cancer and mesothelioma.
Minchom A, Punwani R, Filshie J, Bhosle J, Nimako K, Myerson J, Gunapala R, Popat S, O'Brien ME. Minchom A, et al. Among authors: gunapala r. Eur J Cancer. 2016 Jul;61:102-10. doi: 10.1016/j.ejca.2016.03.078. Epub 2016 May 6. Eur J Cancer. 2016. PMID: 27156228 Clinical Trial.
An unblinded, randomised phase II study of platinum-based chemotherapy with vitamin B12 and folic acid supplementation in the treatment of lung cancer with plasma homocysteine blood levels as a biomarker of severe neutropenic toxicity.
Minchom AR, Saksornchai K, Bhosle J, Gunapala R, Puglisi M, Lu SK, Nimako K, Coward J, Yu KC, Bordi P, Popat S, O'Brien ME. Minchom AR, et al. Among authors: gunapala r. BMJ Open Respir Res. 2014 Dec 11;1(1):e000061. doi: 10.1136/bmjresp-2014-000061. eCollection 2014. BMJ Open Respir Res. 2014. PMID: 25553247 Free PMC article.
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