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CD40L-armed oncolytic herpes simplex virus suppresses pancreatic ductal adenocarcinoma by facilitating the tumor microenvironment favorable to cytotoxic T cell response in the syngeneic mouse model.
Wang R, Chen J, Wang W, Zhao Z, Wang H, Liu S, Li F, Wan Y, Yin J, Wang R, Li Y, Zhang C, Zhang H, Cao Y. Wang R, et al. Among authors: zhao z. J Immunother Cancer. 2022 Jan;10(1):e003809. doi: 10.1136/jitc-2021-003809. J Immunother Cancer. 2022. PMID: 35086948 Free PMC article.
An armed oncolytic virus enhances the efficacy of tumor-infiltrating lymphocyte therapy by converting tumors to artificial antigen-presenting cells in situ.
Ye K, Li F, Wang R, Cen T, Liu S, Zhao Z, Li R, Xu L, Zhang G, Xu Z, Deng L, Li L, Wang W, Stepanov A, Wan Y, Guo Y, Li Y, Wang Y, Tian Y, Gabibov AG, Yan Y, Zhang H. Ye K, et al. Among authors: zhao z. Mol Ther. 2022 Dec 7;30(12):3658-3676. doi: 10.1016/j.ymthe.2022.06.010. Epub 2022 Jun 17. Mol Ther. 2022. PMID: 35715953 Free PMC article.
OX40L-Armed Oncolytic Virus Boosts T-cell Response and Remodels Tumor Microenvironment for Pancreatic Cancer Treatment.
Liu S, Li F, Ma Q, Du M, Wang H, Zhu Y, Deng L, Gao W, Wang C, Liu Y, Zhao Z, Liu H, Wang R, Tian Y, Hu M, Wan Y, Lu W, Zhang M, Zhao M, Cao Y, Zhang H, Wang W, Wang H, Wang Y. Liu S, et al. Among authors: zhao z, zhao m. Theranostics. 2023 Jul 9;13(12):4016-4029. doi: 10.7150/thno.83495. eCollection 2023. Theranostics. 2023. PMID: 37554264 Free PMC article.
TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry.
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H. Wang H, et al. Among authors: zhao z. Cell. 2024 Aug 8;187(16):4261-4271.e17. doi: 10.1016/j.cell.2024.06.016. Epub 2024 Jul 3. Cell. 2024. PMID: 38964329
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