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Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS.
Kandasamy P, Liu Y, Aduda V, Akare S, Alam R, Andreucci A, Boulay D, Bowman K, Byrne M, Cannon M, Chivatakarn O, Shelke JD, Iwamoto N, Kawamoto T, Kumarasamy J, Lamore S, Lemaitre M, Lin X, Longo K, Looby R, Marappan S, Metterville J, Mohapatra S, Newman B, Paik IH, Patil S, Purcell-Estabrook E, Shimizu M, Shum P, Standley S, Taborn K, Tripathi S, Yang H, Yin Y, Zhao X, Dale E, Vargeese C. Kandasamy P, et al. Among authors: lin x. Nucleic Acids Res. 2022 Jun 10;50(10):5401-5423. doi: 10.1093/nar/gkac037. Nucleic Acids Res. 2022. PMID: 35106589 Free PMC article.
Preclinical evaluation of WVE-004, aninvestigational stereopure oligonucleotide forthe treatment of C9orf72-associated ALS or FTD.
Liu Y, Andreucci A, Iwamoto N, Yin Y, Yang H, Liu F, Bulychev A, Hu XS, Lin X, Lamore S, Patil S, Mohapatra S, Purcell-Estabrook E, Taborn K, Dale E, Vargeese C. Liu Y, et al. Among authors: lin x. Mol Ther Nucleic Acids. 2022 Apr 20;28:558-570. doi: 10.1016/j.omtn.2022.04.007. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35592494 Free PMC article.
Influence of inhaled nitric oxide on bronchopulmonary dysplasia in preterm infants with PPHN or HRF at birth: a propensity score matched study.
Huang XR, Wang L, Liang GB, Huang SQ, Feng BY, Zhu L, Fan XF, Yao ML, Zhang J, Wang MJ, Zheng Z, Zhu Y, Duan WL, Li ZK, Mao J, Ma L, Xu FL, Wu F, Wei QF, Liu L, Lin XZ. Huang XR, et al. Among authors: lin xz. Front Pharmacol. 2024 Dec 11;15:1515030. doi: 10.3389/fphar.2024.1515030. eCollection 2024. Front Pharmacol. 2024. PMID: 39726789 Free PMC article.
AYVM to AYMM transition on HER2 exon 20 insertion induces TKI resistance in NSCLC.
Mao S, Liu X, Wang L, Wang Y, Yang S, Jiang T, Li X, Wang Q, Li X, Wu F, Gao G, Chen X, Wu C, Zhang W, Zhang J, Lin X, Zhu X, Li B, Li F, Zhou C, Ren S. Mao S, et al. Among authors: lin x. J Thorac Oncol. 2024 Dec 24:S1556-0864(24)02543-7. doi: 10.1016/j.jtho.2024.12.022. Online ahead of print. J Thorac Oncol. 2024. PMID: 39725168
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