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Selective vulnerabilities in the proteostasis network of castration-resistant prostate cancer.
Shkedi A, Taylor IR, Echtenkamp F, Ramkumar P, Alshalalfa M, Rivera-Márquez GM, Moses MA, Shao H, Karnes RJ, Neckers L, Feng F, Kampmann M, Gestwicki JE. Shkedi A, et al. Among authors: rivera marquez gm. Cell Chem Biol. 2022 Mar 17;29(3):490-501.e4. doi: 10.1016/j.chembiol.2022.01.008. Epub 2022 Feb 1. Cell Chem Biol. 2022. PMID: 35108506 Free PMC article.
Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer.
Moses MA, Kim YS, Rivera-Marquez GM, Oshima N, Watson MJ, Beebe KE, Wells C, Lee S, Zuehlke AD, Shao H, Bingman WE 3rd, Kumar V, Malhotra SV, Weigel NL, Gestwicki JE, Trepel JB, Neckers LM. Moses MA, et al. Among authors: rivera marquez gm. Cancer Res. 2018 Jul 15;78(14):4022-4035. doi: 10.1158/0008-5472.CAN-17-3728. Epub 2018 May 15. Cancer Res. 2018. PMID: 29764864 Free PMC article.
Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer.
Echtenkamp FJ, Ishida R, Rivera-Marquez GM, Maisiak M, Johnson OT, Shrimp JH, Sinha A, Ralph SJ, Nisbet I, Cherukuri MK, Gestwicki JE, Neckers LM. Echtenkamp FJ, et al. Among authors: rivera marquez gm. PNAS Nexus. 2023 Apr 3;2(4):pgad115. doi: 10.1093/pnasnexus/pgad115. eCollection 2023 Apr. PNAS Nexus. 2023. PMID: 37091547 Free PMC article.