Nikula KJ - Search Results

1

Lung-restricted ALK5 inhibition avoids systemic toxicities associated with TGFβ pathway inhibition.

Maher JM, Zhang R, Palanisamy G, Perkins K, Liu L, Brassil P, McNamara A, Lo A, Hughes AD, Kanodia J, Kulyk S, Nikula KJ, Dengler HS, Scandurra A, Lua I, Harstad E. Maher JM, et al. Among authors: nikula kj. Toxicol Appl Pharmacol. 2022 Mar 1;438:115905. doi: 10.1016/j.taap.2022.115905. Epub 2022 Feb 3. Toxicol Appl Pharmacol. 2022. PMID: 35122773 Free article.

2

Symposium Summary: "Breathe In, Breathe Out, Its Easy: What You Need to Know About Developing Inhaled Drugs".

Tepper JS, Kuehl PJ, Cracknell S, Nikula KJ, Pei L, Blanchard JD. Tepper JS, et al. Among authors: nikula kj. Int J Toxicol. 2016 Jul;35(4):376-92. doi: 10.1177/1091581815624080. Epub 2016 Feb 7. Int J Toxicol. 2016. PMID: 26857693

3

Enhanced pulmonary epithelial replication and axial airway mucosubstance changes in F344 rats exposed short-term to mainstream cigarette smoke.

March TH, Kolar LM, Barr EB, Finch GL, Ménache MG, Nikula KJ. March TH, et al. Among authors: nikula kj. Toxicol Appl Pharmacol. 1999 Dec 1;161(2):171-9. doi: 10.1006/taap.1999.8798. Toxicol Appl Pharmacol. 1999. PMID: 10581211

4

Effect of chronic cigarette smoke exposure on lung clearance of tracer particles inhaled by rats.

Finch GL, Nikula KJ, Chen BT, Barr EB, Chang IY, Hobbs CH. Finch GL, et al. Among authors: nikula kj. Fundam Appl Toxicol. 1995 Jan;24(1):76-85. doi: 10.1006/faat.1995.1009. Fundam Appl Toxicol. 1995. PMID: 7713345

5

Long-Term Nonclinical Pulmonary Safety Assessment of Afrezza, a Novel Insulin Inhalation Powder.

Greene SF, Nikula KJ, Poulin D, McInally K, Reynolds JA. Greene SF, et al. Among authors: nikula kj. Toxicol Pathol. 2021 Feb;49(2):334-348. doi: 10.1177/0192623320960420. Epub 2020 Oct 12. Toxicol Pathol. 2021. PMID: 33043802

6

Intermittent convection-enhanced delivery of GDNF into rhesus monkey putamen: absence of local or cerebellar toxicity.

Luz M, Allen PC, Bringas J, Boiko C, Stockinger DE, Nikula KJ, Lewis O, Woolley M, Fibiger HC, Bankiewicz K, Mohr E. Luz M, et al. Among authors: nikula kj. Arch Toxicol. 2018 Jul;92(7):2353-2367. doi: 10.1007/s00204-018-2222-z. Epub 2018 May 22. Arch Toxicol. 2018. PMID: 29785638 Free PMC article.

7

In vitro evidence of cellular adaptation to ozone toxicity in the rat trachea.

Nikula KJ, Wilson DW, Dungworth DL, Plopper CG. Nikula KJ, et al. Toxicol Appl Pharmacol. 1988 May;93(3):394-402. doi: 10.1016/0041-008x(88)90042-7. Toxicol Appl Pharmacol. 1988. PMID: 3368918 Free PMC article.

8

BSTP Review of 12 Case Studies Discussing the Challenges, Pathology, Immunogenicity, and Mechanisms of Inhaled Biologics.

Hall AP, Tepper JS, Boyle MH, Cary MG, Flandre TG, Piaia A, Tarnow I, Macri NP, Freke MC, Nikula KJ, Paul GR, Cauvin A, Gregori M, Haworth R, Naylor S, Price M, Robinson IN, Allen A, Gelzleichter T, Hohlbaum AM, Manetz S, Wolfreys A, Colman K, Fleurance R, Jones D, Mukaratirwa S. Hall AP, et al. Among authors: nikula kj. Toxicol Pathol. 2021 Feb;49(2):235-260. doi: 10.1177/0192623320976094. Epub 2021 Jan 18. Toxicol Pathol. 2021. PMID: 33455525 Review.

9

Effects of strain and treatment with inhaled aII-trans-retinoic acid on cigarette smoke-induced pulmonary emphysema in mice.

March TH, Bowen LE, Finch GL, Nikula KJ, Wayne BJ, Hobbs CH. March TH, et al. Among authors: nikula kj. COPD. 2005 Sep;2(3):289-302. COPD. 2005. PMID: 17146994

10

Failure of cigarette smoke to induce or promote lung cancer in the A/J mouse.

Finch GL, Nikula KJ, Belinsky SA, Barr EB, Stoner GD, Lechner JF. Finch GL, et al. Among authors: nikula kj. Cancer Lett. 1996 Feb 6;99(2):161-7. doi: 10.1016/0304-3835(95)04059-5. Cancer Lett. 1996. PMID: 8616820

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