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A comprehensive survey of the mutagenic impact of common cancer cytotoxics.
Szikriszt B, Póti Á, Pipek O, Krzystanek M, Kanu N, Molnár J, Ribli D, Szeltner Z, Tusnády GE, Csabai I, Szallasi Z, Swanton C, Szüts D. Szikriszt B, et al. Genome Biol. 2016 May 9;17:99. doi: 10.1186/s13059-016-0963-7. Genome Biol. 2016. PMID: 27161042 Free PMC article.
Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.
Zámborszky J, Szikriszt B, Gervai JZ, Pipek O, Póti Á, Krzystanek M, Ribli D, Szalai-Gindl JM, Csabai I, Szallasi Z, Swanton C, Richardson AL, Szüts D. Zámborszky J, et al. Among authors: szikriszt b. Oncogene. 2017 Feb 9;36(6):746-755. doi: 10.1038/onc.2016.243. Epub 2016 Jul 25. Oncogene. 2017. PMID: 27452521 Free PMC article.
Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions.
Zámborszky J, Szikriszt B, Gervai JZ, Pipek O, Póti Á, Krzystanek M, Ribli D, Szalai-Gindl JM, Csabai I, Szallasi Z, Swanton C, Richardson AL, Szüts D. Zámborszky J, et al. Among authors: szikriszt b. Oncogene. 2017 Aug 31;36(35):5085-5086. doi: 10.1038/onc.2017.213. Epub 2017 Jun 26. Oncogene. 2017. PMID: 28650471 Free PMC article.
Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents.
Póti Á, Gyergyák H, Németh E, Rusz O, Tóth S, Kovácsházi C, Chen D, Szikriszt B, Spisák S, Takeda S, Szakács G, Szallasi Z, Richardson AL, Szüts D. Póti Á, et al. Among authors: szikriszt b. Genome Biol. 2019 Nov 14;20(1):240. doi: 10.1186/s13059-019-1867-0. Genome Biol. 2019. PMID: 31727117 Free PMC article.