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Page 1
BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.
Berres ML, Lim KP, Peters T, Price J, Takizawa H, Salmon H, Idoyaga J, Ruzo A, Lupo PJ, Hicks MJ, Shih A, Simko SJ, Abhyankar H, Chakraborty R, Leboeuf M, Beltrão M, Lira SA, Heym KM, Bigley V, Collin M, Manz MG, McClain K, Merad M, Allen CE. Berres ML, et al. Among authors: abhyankar h. J Exp Med. 2014 Apr 7;211(4):669-83. doi: 10.1084/jem.20130977. Epub 2014 Mar 17. J Exp Med. 2014. PMID: 24638167 Free PMC article.
Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.
Chakraborty R, Hampton OA, Shen X, Simko SJ, Shih A, Abhyankar H, Lim KP, Covington KR, Trevino L, Dewal N, Muzny DM, Doddapaneni H, Hu J, Wang L, Lupo PJ, Hicks MJ, Bonilla DL, Dwyer KC, Berres ML, Poulikakos PI, Merad M, McClain KL, Wheeler DA, Allen CE, Parsons DW. Chakraborty R, et al. Among authors: abhyankar h. Blood. 2014 Nov 6;124(19):3007-15. doi: 10.1182/blood-2014-05-577825. Epub 2014 Sep 8. Blood. 2014. PMID: 25202140 Free PMC article.
Differentiating skin-limited and multisystem Langerhans cell histiocytosis.
Simko SJ, Garmezy B, Abhyankar H, Lupo PJ, Chakraborty R, Lim KP, Shih A, Hicks MJ, Wright TS, Levy ML, McClain KL, Allen CE. Simko SJ, et al. Among authors: abhyankar h. J Pediatr. 2014 Nov;165(5):990-6. doi: 10.1016/j.jpeds.2014.07.063. Epub 2014 Oct 21. J Pediatr. 2014. PMID: 25441388 Free PMC article.
Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis.
Chakraborty R, Burke TM, Hampton OA, Zinn DJ, Lim KP, Abhyankar H, Scull B, Kumar V, Kakkar N, Wheeler DA, Roy A, Poulikakos PI, Merad M, McClain KL, Parsons DW, Allen CE. Chakraborty R, et al. Among authors: abhyankar h. Blood. 2016 Nov 24;128(21):2533-2537. doi: 10.1182/blood-2016-08-733790. Epub 2016 Oct 11. Blood. 2016. PMID: 27729324 Free PMC article.
Activating MAPK1 (ERK2) mutation in an aggressive case of disseminated juvenile xanthogranuloma.
Chakraborty R, Hampton OA, Abhyankar H, Zinn DJ, Grimes A, Skull B, Eckstein O, Mahmood N, Wheeler DA, Lopez-Terrada D, Peters TL, Hicks JM, Elghetany T, Krance R, Poulikakos PI, Merad M, McClain KL, Allen CE, Parsons DW. Chakraborty R, et al. Among authors: abhyankar h. Oncotarget. 2017 Jul 11;8(28):46065-46070. doi: 10.18632/oncotarget.17521. Oncotarget. 2017. PMID: 28512266 Free PMC article.
A genome-wide association study of LCH identifies a variant in SMAD6 associated with susceptibility.
Peckham-Gregory EC, Chakraborty R, Scheurer ME, Belmont JW, Abhyankar H, Sengal AG, Scull BP, Eckstein O, Zinn DJ, Mayer L, Shih A, Merad M, Parsons DW, McClain KL, Lupo PJ, Allen CE. Peckham-Gregory EC, et al. Among authors: abhyankar h. Blood. 2017 Nov 16;130(20):2229-2232. doi: 10.1182/blood-2017-08-800565. Epub 2017 Sep 21. Blood. 2017. PMID: 28935696 Free PMC article. No abstract available.
CNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH-associated neurodegeneration and mass lesions.
McClain KL, Picarsic J, Chakraborty R, Zinn D, Lin H, Abhyankar H, Scull B, Shih A, Lim KPH, Eckstein O, Lubega J, Peters TL, Olea W, Burke T, Ahmed N, Hicks MJ, Tran B, Jones J, Dauser R, Jeng M, Baiocchi R, Schiff D, Goldman S, Heym KM, Wilson H, Carcamo B, Kumar A, Rodriguez-Galindo C, Whipple NS, Campbell P, Murdoch G, Kofler J, Heales S, Malone M, Woltjer R, Quinn JF, Orchard P, Kruer MC, Jaffe R, Manz MG, Lira SA, Parsons DW, Merad M, Man TK, Allen CE. McClain KL, et al. Among authors: abhyankar h. Cancer. 2018 Jun 15;124(12):2607-2620. doi: 10.1002/cncr.31348. Epub 2018 Apr 6. Cancer. 2018. PMID: 29624648 Free PMC article.
Circulating CD1c+ myeloid dendritic cells are potential precursors to LCH lesion CD1a+CD207+ cells.
Lim KPH, Milne P, Poidinger M, Duan K, Lin H, McGovern N, Abhyankar H, Zinn D, Burke TM, Eckstein OS, Chakraborty R, Sengal A, Scull B, Newell E, Merad M, McClain KL, Man TK, Ginhoux F, Collin M, Allen CE. Lim KPH, et al. Among authors: abhyankar h. Blood Adv. 2020 Jan 14;4(1):87-99. doi: 10.1182/bloodadvances.2019000488. Blood Adv. 2020. PMID: 31899802 Free PMC article.
29 results