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PHLPP1 promotes neutral lipid accumulation through AMPK/ChREBP-dependent lipid uptake and fatty acid synthesis pathways.
Balamurugan K, Medishetti R, Kotha J, Behera P, Chandra K, Mavuduru VA, Joshi MB, Samineni R, Katika MR, Ball WB, Thondamal M, Challa A, Chatti K, Parsa KVL. Balamurugan K, et al. Among authors: chatti k. iScience. 2022 Jan 12;25(2):103766. doi: 10.1016/j.isci.2022.103766. eCollection 2022 Feb 18. iScience. 2022. PMID: 35141506 Free PMC article.
Ligand/PTC-free intramolecular Heck reaction: synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo.
Babu PV, Mukherjee S, Deora GS, Chennubhotla KS, Medisetti R, Yellanki S, Kulkarni P, Sripelly S, Parsa KV, Chatti K, Mukkanti K, Pal M. Babu PV, et al. Among authors: chatti k. Org Biomol Chem. 2013 Oct 21;11(39):6680-5. doi: 10.1039/c3ob41504j. Epub 2013 Aug 29. Org Biomol Chem. 2013. PMID: 23986357
PdCl2-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitor.
Thirupataiah B, Mounika G, Reddy GS, Kumar JS, Hossain KA, Medishetti R, Samarpita S, Rasool M, Mudgal J, Mathew JE, Shenoy GG, Rao CM, Chatti K, Parsa KVL, Pal M. Thirupataiah B, et al. Among authors: chatti k. Eur J Med Chem. 2021 Oct 5;221:113514. doi: 10.1016/j.ejmech.2021.113514. Epub 2021 May 6. Eur J Med Chem. 2021. PMID: 33992926
CuCl2-catalyzed inexpensive, faster and ligand/additive free synthesis of isoquinolin-1(2H)-one derivatives via the coupling-cyclization strategy: Evaluation of a new class of compounds as potential PDE4 inhibitors.
Thirupataiah B, Mounika G, Sujeevan Reddy G, Sandeep Kumar J, Kapavarapu R, Medishetti R, Mudgal J, Mathew JE, Shenoy GG, Mallikarjuna Rao C, Chatti K, V L Parsa K, Pal M. Thirupataiah B, et al. Among authors: chatti k. Bioorg Chem. 2021 Oct;115:105265. doi: 10.1016/j.bioorg.2021.105265. Epub 2021 Aug 13. Bioorg Chem. 2021. PMID: 34426160
CRISPR-Cas9-induced gene knockout in zebrafish.
Medishetti R, Balamurugan K, Yadavalli K, Rani R, Sevilimedu A, Challa AK, Parsa K, Chatti K. Medishetti R, et al. Among authors: chatti k. STAR Protoc. 2022 Oct 26;3(4):101779. doi: 10.1016/j.xpro.2022.101779. eCollection 2022 Dec 16. STAR Protoc. 2022. PMID: 36317180 Free PMC article.
Protocol to evaluate hyperlipidemia in zebrafish larvae.
Balamurugan K, Medishetti R, Rao P, K RV, Chatti K, Parsa KVL. Balamurugan K, et al. Among authors: chatti k. STAR Protoc. 2022 Nov 7;3(4):101819. doi: 10.1016/j.xpro.2022.101819. eCollection 2022 Dec 16. STAR Protoc. 2022. PMID: 36386866 Free PMC article.
62 results