Davtyan H - Search Results

1

The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model.

Claes C, England WE, Danhash EP, Kiani Shabestari S, Jairaman A, Chadarevian JP, Hasselmann J, Tsai AP, Coburn MA, Sanchez J, Lim TE, Hidalgo JLS, Tu C, Cahalan MD, Lamb BT, Landreth GE, Spitale RC, Blurton-Jones M, Davtyan H. Claes C, et al. Among authors: davtyan h. Alzheimers Dement. 2022 Oct;18(10):1765-1778. doi: 10.1002/alz.12577. Epub 2022 Feb 9. Alzheimers Dement. 2022. PMID: 35142046 Free PMC article.

2

Epitope-based DNA vaccine for Alzheimer's disease: translational study in macaques.

Evans CF, Davtyan H, Petrushina I, Hovakimyan A, Davtyan A, Hannaman D, Cribbs DH, Agadjanyan MG, Ghochikyan A. Evans CF, et al. Among authors: davtyan h, davtyan a. Alzheimers Dement. 2014 May;10(3):284-95. doi: 10.1016/j.jalz.2013.04.505. Epub 2013 Jul 31. Alzheimers Dement. 2014. PMID: 23916838 Free PMC article.

3

The MultiTEP platform-based Alzheimer's disease epitope vaccine activates a broad repertoire of T helper cells in nonhuman primates.

Davtyan H, Ghochikyan A, Petrushina I, Hovakimyan A, Davtyan A, Cribbs DH, Agadjanyan MG. Davtyan H, et al. Among authors: davtyan a. Alzheimers Dement. 2014 May;10(3):271-83. doi: 10.1016/j.jalz.2013.12.003. Epub 2014 Feb 20. Alzheimers Dement. 2014. PMID: 24560029 Free PMC article.

4

The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function.

Marsh SE, Abud EM, Lakatos A, Karimzadeh A, Yeung ST, Davtyan H, Fote GM, Lau L, Weinger JG, Lane TE, Inlay MA, Poon WW, Blurton-Jones M. Marsh SE, et al. Among authors: davtyan h. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1316-25. doi: 10.1073/pnas.1525466113. Epub 2016 Feb 16. Proc Natl Acad Sci U S A. 2016. PMID: 26884167 Free PMC article.

5

Comparison of Efficacy of Preventive and Therapeutic Vaccines Targeting the N Terminus of β-Amyloid in an Animal Model of Alzheimer's Disease.

Petrushina I, Davtyan H, Hovakimyan A, Davtyan A, Passos GF, Cribbs DH, Ghochikyan A, Agadjanyan MG. Petrushina I, et al. Among authors: davtyan h, davtyan a. Mol Ther. 2017 Jan 4;25(1):153-164. doi: 10.1016/j.ymthe.2016.10.002. Epub 2017 Jan 4. Mol Ther. 2017. PMID: 28129111 Free PMC article.

6

Human Neural Progenitor Transplantation Rescues Behavior and Reduces α-Synuclein in a Transgenic Model of Dementia with Lewy Bodies.

Goldberg NRS, Marsh SE, Ochaba J, Shelley BC, Davtyan H, Thompson LM, Steffan JS, Svendsen CN, Blurton-Jones M. Goldberg NRS, et al. Among authors: davtyan h. Stem Cells Transl Med. 2017 Jun;6(6):1477-1490. doi: 10.1002/sctm.16-0362. Epub 2017 Feb 22. Stem Cells Transl Med. 2017. PMID: 28225193 Free PMC article.

7

MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice.

Davtyan H, Chen WW, Zagorski K, Davis J, Petrushina I, Kazarian K, Cribbs DH, Agadjanyan MG, Blurton-Jones M, Ghochikyan A. Davtyan H, et al. Vaccine. 2017 Apr 11;35(16):2015-2024. doi: 10.1016/j.vaccine.2017.03.020. Epub 2017 Mar 18. Vaccine. 2017. PMID: 28320590 Free PMC article.

8

Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency.

Agadjanyan MG, Zagorski K, Petrushina I, Davtyan H, Kazarian K, Antonenko M, Davis J, Bon C, Blurton-Jones M, Cribbs DH, Ghochikyan A. Agadjanyan MG, et al. Among authors: davtyan h. Mol Neurodegener. 2017 May 5;12(1):33. doi: 10.1186/s13024-017-0172-1. Mol Neurodegener. 2017. PMID: 28472993 Free PMC article.

9

MultiTEP platform-based DNA vaccines for alpha-synucleinopathies: preclinical evaluation of immunogenicity and therapeutic potency.

Davtyan H, Zagorski K, Petrushina I, Kazarian K, Goldberg NRS, Petrosyan J, Blurton-Jones M, Masliah E, Cribbs DH, Agadjanyan MG, Ghochikyan A. Davtyan H, et al. Neurobiol Aging. 2017 Nov;59:156-170. doi: 10.1016/j.neurobiolaging.2017.08.006. Epub 2017 Aug 10. Neurobiol Aging. 2017. PMID: 28870518 Free PMC article.

10

Development and validation of a simplified method to generate human microglia from pluripotent stem cells.

McQuade A, Coburn M, Tu CH, Hasselmann J, Davtyan H, Blurton-Jones M. McQuade A, et al. Among authors: davtyan h. Mol Neurodegener. 2018 Dec 22;13(1):67. doi: 10.1186/s13024-018-0297-x. Mol Neurodegener. 2018. PMID: 30577865 Free PMC article.

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